Results 51 to 60 of about 441,335 (282)

High-Detail Fault Segmentation: Deep Insight into the Anatomy of the 1983 Borah Peak Earthquake Rupture Zone (Mw 6.9, Idaho, USA)

open access: yesLithosphere, 2022
Following observations made in a survey campaign along the Lost River Fault (Idaho, USA) in 2019, we integrate both original and previously published data to obtain a detailed segmentation of the fault sections that failed in the 1983 Borah Peak ...
Simone Bello   +6 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

The Influence of Fault Geometrical Complexity on Surface Rupture Length

open access: yesGeophysical Research Letters
Propagating earthquakes must overcome geometrical complexity on fault networks to grow into large, surface rupturing events. We map step‐overs, bends, gaps, splays, and strands of length scales ∼100–500 m from the surface ruptures of 31 strike‐slip ...
A. M. Rodriguez Padilla   +5 more
doaj   +1 more source

On the determination of the earthquake slip distribution via linear programming techniques [PDF]

open access: yes, 2012
The description that one can have of the seismic source is the mani- festation of an imagined model, obviously outlined from Physic Theories and supported by mathematical methods.
Bushenkov, V., Caldeira, B., Smirnov, G.
core  

Caspase-8 binding to cardiolipin in giant unilamellar vesicles provides a functional docking platform for bid [PDF]

open access: yes, 2013
Caspase-8 is involved in death receptor-mediated apoptosis in type II cells, the proapoptotic programme of which is triggered by truncated Bid. Indeed, caspase-8 and Bid are the known intermediates of this signalling pathway.
AH Stegh   +73 more
core   +6 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Earthquake-induced fissures and their formation mechanisms in the 2023 MS 6.2 Jishishan Earthquake

open access: yesDizhi lixue xuebao
Objective  Seismic fissures, landslides and mudflows are common secondary hazards of earthquakes. Following the occurrence of moderately strong earthquakes, detailed investigations of landslides and mudflows are usually conducted, but earthquake-induced ...
ZHANG Bo   +6 more
doaj   +1 more source

Normal fault earthquakes or graviquakes [PDF]

open access: yes, 2015
Earthquakes are dissipation of energy throughout elastic waves. Canonically is the elastic energy accumulated during the interseismic period. However, in crustal extensional settings, gravity is the main energy source for hangingwall fault collapsing ...
Carminati, Eugenio Ambrogio Maria   +3 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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