Results 31 to 40 of about 6,728,043 (242)
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Journal of Magnesium and AlloysMg-Li alloys with high lithium concentrations possess a lightweight body-centered cubic (BCC) matrix structure (β-Li). Interspersed eutectics (primarily the reticulated I-phase) often form along phase boundaries (PBs) and grain boundaries (GBs) which ...
Yu Wang +8 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Characterising the impact of surface integrity on the fatigue behaviour of a shot-peened connecting rod [PDF]
, 2014 The present study focuses on analysing and modelling the influence on fatigue behaviour of the surface of a hot-forged C70 connecting rod which undergoes a shot-blasting treatment.
PESSARD, Etienne +3 more
core
, 2022 Effects of surface modifications on the adhesive joint of carbon fibre reinforced polymer (CFRP) were investigated. CFRP surfaces were treated with traditional methods, such as acetone cleaning, sanding, grit blasting and peel ply.
Gunputh, U. +5 more
core +1 more source
Construction MaterialsThe study is motivated by the application of dry finish milling for post-build processing of additive Ti6Al4V blanks, since the use of neither lubricant nor coolants has been attracting increasing attention due to its environmental benefits, non-toxicity,
Sergey V. Panin +5 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Design of fatigue strength on adhesive interface between metal and resin in Resin-molded structure
Nihon Kikai Gakkai ronbunshu, 2014 For the stabilization of insulation performance in the resin-molded insulators, strong adhesion between the resin and metal is required. In this paper, design method of fatigue strength on adhesive interface between metal and resin in consideration of ...
Miki YAMAZAKI
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source