Results 31 to 40 of about 112,686 (262)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Comparison of methods of surface strengthening of machine parts by coatings

Вісник Черкаського державного технологічного університету, 2021
The article analyzes and compares the most common methods of surface hardening of machine parts with coatings. It is noted that by using protective coatings it is possible to solve a number of scientific and technical problems of mechanical engineering, providing a comprehensive rational use of the properties of the base of the part and the properties ...
Volodymyr Posuvailo, Maksym Shovkoplias, Mykola Romaniv, Volodymyr Malinin   +3 more
openaire   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Effect of aggregate surface strengthening on compressive damage of pre-placed coal gangue cemented backfill

Meitan kexue jishu
Coal gangue is the main solid waste derived from coal mining. Its disadvantages, such as significant quality fluctuation, high crushing value, large water absorption, and poor stability, limit the large-scale application of backfilling in goaf, which has
Jiaxu JIN, Xiaowei GU, Mingxu LI, Zhifa QIN, Tao LIU, Pengfei WU, Shenghao ZUO   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Improvement of surface properties of alloy constructional steel with ultrasonic composite strengthening modification

Results in Materials, 2022
The key components of the automatic gun are subjected to the severe working condition of high temperature, transient state and continuous strong impact load in the shooting process, the surface of which using the alloy constructional steel is prone to ...
Dan Liu, Shiming Zhang, Yalin Shen, Lun Lin, Yongqiang Yuan, Chao Meng, Xiaohui Li   +6 more
doaj   +1 more source

THE OPTIMIZATION OF THE MODEL OF THE STRENGTHENED LAYER BY THE SURFACE STRENGTHENING

Вестник Донского государственного технического университета, 2009
The parameters of the imitative model of multilayer conductive ferromagnetic media to achieve the optimal precision of modeling are determined. The experimental investigation of the distribution of physicomechanical and electromagnetic properties along the thickness of the sample have been carried out.
А.А. LAVRENTYEV, I.Е. ROGOV, S.D. ANISIMOV, V.S. KOVALEVA   +3 more
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Research Status and Trend of M50 Bearing Steel Surface Strengthening Technology [PDF]

Cailiao Baohu
Bearings，regarded as the “heart” of aircraft engines，operate under extreme conditions involving high temperatures，high pressures，and high speeds，with fatigue being their primary failure mode.To enhance the performance of aerospace bearings and ...
ZHANG Hao, PAN Yongzhi, YANG Yanzhao, ZHUANG Qikai, LIANG Hao, MEN Xiuhua
doaj   +1 more source