Results 41 to 50 of about 112,686 (262)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Load-adaptive tribology of in-situ compositionally graded Ti-6Al-4V/graphite composites produced by powder metallurgy

Materials Research Express
This study investigates the tribological behaviour of an in situ fabricated compositionally graded Ti-6Al-4V/graphite surface architecture produced by powder metallurgy, in which a graphite-containing surface layer (5 wt% graphite) is metallurgically ...
Yasemin Yıldıran Avcu, Furkan Tunç
doaj   +1 more source

The Effects of Various Silicate Coatings on the Durability of Concrete: Mechanisms and Implications

Buildings
Silicate solutions can improve the durability of concrete conveniently and effectively. To horizontally compare the enhancement effects of different composite silicate solutions, three types of silicate surface treatment agents were prepared by using ...
Jinfu Li, Jiale Song, Shuheng Zhang, Wei Liu, Zhaokuan Cui, Weiguang Li   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Surface shot peening of cast SiCw/Al composites

Heat Treatment and Surface Engineering
The surface shot peening treatment was carried out on the as-cast SiCw/Al composites, and the distribution of the residual stresses in the surface matrix was measured, the X-ray diffraction method for the yield strength of the surface matrix of the ...
Xing Liu, Teng-Yi Meng, Wen-Bo Li, Chuan-Hai Jiang   +3 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Research Progress on Fatigue Damage and Surface Strengthening Technology of Titanium Alloys for Aerospace Applications

Metals
As advanced structural materials, titanium alloys have found extensive applications in aerospace, medical devices, and precision electronics industries, serving as critical components for achieving lightweight designs in high-end equipment.
Weiming Li, Shaoqing Wang, Xiao Yang, Hongbo Duan, Yimeng Wang, Zhong Yang   +5 more
doaj   +1 more source

STUDY ON THE EFFECT OF ROLLING STRENGTHENING ON THE SURFACE INTEGRITY OF 45 STEEL THREAD ROOT

Jixie qiangdu, 2022
The self-made thread root rolling strengthening device based on common lathe CA6140 was used to perform rolling strengthening process on 45 steel thread samples.
WANG Dong, LU XinXi, ZHAO JingWen, LIN HongXu, ZHANG Meng   +4 more
doaj  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Flexural and Shear Strengthening of High-Strength Concrete Beams Using near Surface Basalt Fiber Bars

Infrastructures
Strengthening of reinforced concrete (RC) structures has become a primary challenge in civil engineering. Different materials and procedures have been used in order to repair or strengthen RC structures.
Ahmed Ashteyat, Ala’ Taleb Obaidat, Ahmad Al-Khreisat, Mu’tasime Abdel-Jaber   +3 more
doaj   +1 more source