Results 111 to 120 of about 96,439 (302)

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

Interim Report on Studies of the Mw ~7.9 Earthquake of 3 May 2006, Kingdom of Tonga [PDF]

, 2018
The very large and rare Mw ~7.9 Earthquake of 3 May 2006 in the Kingdom of Tonga aroused great interest among both Tongan scientists and their colleagues in Australia, New Zealand, and the United States.
Beavan, John, Bevis, Michael G., Cummins, Phil, Fatai, Tevita, Heeszel, David, Kendrick, Eric, Lahtinen, Anna-Lisa, Mafi, Kelepi, Malolo, Tevita, Moala, ‘Apai, Nonu, Sione, Shore, Patrick, Taylor, Frederick W., Wallace, Laura, Whatman, James, Wiens, Douglas   +15 more
core   +1 more source

The Floor‐Ceiling‐Chip, or 2 × 2D = Pseudo‐3D—Approaching 3D Cell Morphology and Organization between Two Opposing 2D Substrates with Cell‐Adhesive Protein Micropatterns

Advanced Healthcare Materials, EarlyView.
Here, we present a novel 3D cell patterning and culture platform. The “Floor‐Ceiling‐Chip” (FC‐Chip) consists of two opposing track‐etched membranes, creating a pseudo‐3D microenvironment for the cells in between. By providing the membranes with micropatterned cell‐adhesive islands of varying geometries and sizes, the FC‐Chip enables control over cell ...
Urandelger Tuvshindorj, Francesca Giacomini, Esra Güben Kaçmaz, Tim ten Brink, Lorenzo Moroni, Zeinab Tahmasebi Birgani, Clemens van Blitterswijk, Pamela Habibović, Stefan Giselbrecht, Jan de Boer, Roman Truckenmüller   +10 more
wiley   +1 more source

Temperature Structure and Atmospheric Circulation of Dry, Tidally Locked Rocky Exoplanets

, 2016
Next-generation space telescopes will observe the atmospheres of rocky planets orbiting nearby M-dwarfs. Understanding these observations will require well-developed theory in addition to numerical simulations.
Abbot, Dorian S., Koll, Daniel D. B.
core   +1 more source

The case for dynamic subsidence of the U.S. east coast since the Eocene [PDF]

, 2008
The dynamic subsidence of the United States east coast is addressed using the discrepancy between regional and global estimates of sea level, elevation of paleoshorelines, and adjoint models of mantle convection that assimilate plate motions and seismic ...
Gurnis, Michael, Liu, Lijun, Müller, R. Dietmar, Spasojević, Sonja   +3 more
core   +1 more source

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

Advanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu, Guoying Wang, Yang Zhang, Bingyang Shi, Ming Li   +4 more
wiley   +1 more source

Micromechanical computational modeling of reservoir compaction and surface subsidence

Matemática Contemporânea, 2000
The authors generalize computational dual porosity models developed for the case where the solid matrix undergoes elastic deformations. Variational formulation and the corrosponding two-level finite element approximations are proposed to discretize the dual porosity system.
João Guerreiro, Marcio Murad, Abimael Loula   +2 more
openaire   +2 more sources

SiO2‐CaOCME/Poly(Tetrahydrofuran)/Poly(Caprolactone) 3D‐Printed Scaffolds Drive Human‐Bone Marrow Stromal Cell Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
3D printed hybrid scaffolds combining bioactive silica–calcium chemistry with elastic polymers guide human bone stem cells to form bone. The scaffolds support cell survival, organization, and invasion while releasing osteogenic ions. Together, architecture and composition drive bone‐specific gene expression, extracellular matrix organization, and ...
David R. Sory, Agathe C.M. Heyraud, Julian R. Jones, Sara M. Rankin   +3 more
wiley   +1 more source

Verification of Various Surface Subsided Results with Surface Subsidence Theories. Caving and subsidence of rock strata by wall type mining. (2nd Report).

Shigen-to-Sozai, 2000
The author elaborated the results of studies on Surface Subsidence in various coal fileds in Japan(Kushiro), England(NCB collieries) and Republic of South Africa (Sigma). Firstly, the author analysed the sphere at goaf area where fallen rock debris solidified at bottom part while upper rock strata deteriorated by cracking caused by earth pressure.
openaire   +2 more sources

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

Advanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka, Shohei Morikawa, Shigehito Osawa   +2 more
wiley   +1 more source