This study shows that amyloid fibrils form nematic condensates via liquid–liquid crystalline phase separation (LLCPS). With increasing pH, this transition shifts toward disordered condensates formed through liquid–liquid phase separation (LLPS), in which birefringence with lack of a coherent nematic field symmetry originates from enthalpic fibril ...
Milad Radiom, Raffaele Mezzenga
wiley +1 more source
Analysis of the failure state of the Cenozoic clay layer in thin bedrock coal seam mining: A case study of Sanyuan coal mine. [PDF]
Wu G, Wang M, Wang L.
europepmc +1 more source
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source
Research on ground deformation induced by large caisson construction at the Zhuchong pumping station in Xinyang, China. [PDF]
Xu Z +5 more
europepmc +1 more source
Boosting Photo‐Pyroelectric Effect via Tunable Polarization and Interfacial Defect Engineering
This study reports Ba(Ti0.85Zr0.15)O3 nanocatalysts with enhanced polarization and oxygen‐vacancy‐rich interfaces for efficient NIR‐II photo‐pyroelectric therapy. Zr doping boosts the pyroelectric coefficient and accelerates polarization switching, while oxygen vacancies improve photothermal conversion and surface reactivity.
Yanli Huang +13 more
wiley +1 more source
Spatiotemporal deformation trend assessment based on ICOPS and ICA methods using multitemporal InSAR data in industrial development zones. [PDF]
Fadhillah MF +8 more
europepmc +1 more source
Cross‐Platform Biosensing of Immune Receptors Using Peptide‐Functionalized Graphene
A peptide‐functionalized graphene biosensor enables sensitive and selective detection of living immune cells. Targeting Formyl‐Peptide Receptor 2 (FPR2), the assay is demonstrated on model cells and primary human neutrophils. The same assay is applied to two complementary platforms: graphene‐enhanced surface plasmon resonance for optical benchmarking ...
Ahmar Hasnain +5 more
wiley +1 more source
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Structural design and biomechanical analysis of anti- subsidence gradient porous artificial vertebrae combined with a topology framework. [PDF]
Shang P, Wu X, Li R, Ma B, Wu H, Liu Y.
europepmc +1 more source

