Results 131 to 140 of about 8,878,259 (313)

Digitized log file, Utah Geological Survey Well Number U068

open access: yes, 2008
This log was digitized by the Utah Geological Survey from image files (.tiff) compiled by the Utah Division of Oil, Gas, and ...
Digitized by the Utah Geological Survey
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Geological survey of Great Britain (England and Wales) [cartographic material] : solid and drift /

open access: yes, 1970
Subtitle varies: Solid geology and solid and drift geology, drift geology, solid and drift geology, solid with drift geology, solid and drift, solid.; Relief shown by contours, hachures, and spot heights. Depths shown by contours.; Title varies: 1:50,000
Great Britain. Ordnance Survey.
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A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Geological Survey of Victoria. No. 5 [cartographic material]

open access: yes
Caption title.; Quarter sheet 5SW is a geological map centred on a mountainous region adjacent to the parish of Rochford in the county of Bourke with cadastral details. Includes nine short notes in the top left margin.
Geological Survey of Victoria.
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Alberga, South Australia [cartographic material].

open access: yes, 1942
1st ed. Shows telephone and power lines, electric power stations, roads, railways and aerodromes.; Relief shown by hachures and spot heights.; "This map is compiled from the latest Commonwealth and State information and is not the result of precise ...
Australia. Army. Survey Corps.
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Geological survey of Great Britain (England & Wales) [cartographic material] /

open access: yes
Various ed. Geological series of England and Wales with relief shown by contours and spot heights.; Title varies: Geological survey of England and Wales.; Some sheets published for the Institute of Geological Sciences.; Original geological survey carried
Great Britain. Ordnance Survey.
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Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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