Results 141 to 150 of about 8,878,259 (313)

Avon Downs, Northern Territory [cartographic material].

open access: yes, 1942
1st ed. "Drawn and Reproduced by L.H.Q. (Aust.) Cartographic Company. 1942."; Catalogue record generated as part of a batch load.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map ...
Australia. Army. Survey Corps.
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

La Grange, Western Australia [cartographic material].

open access: yes, 1942
1st ed. "Printed by A.H.Q. Cartographic Company 1942."; Catalogue record generated as part of a batch load.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map ...
Australia. Army. Survey Corps.
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Exmouth Gulf, Western Australia [cartographic material].

open access: yes, 1942
1st ed. "Printed by A.H.Q. Cartographic Company 1942."; Catalogue record generated as part of a batch load.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map ...
Australia. Army. Survey Corps.
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Caledon Bay, Northern Territory [cartographic material].

open access: yes, 1942
2nd ed. "Printed by A.H.Q. Cartographic Company 1942."; Catalogue record generated as part of a batch load.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map ...
Australia. Army. Survey Corps.
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

A Survey on curve and surface fairing

open access: yes, 1998
Sculptured or free-form surface design is a broadly used tool in industry. This report studies the existing automatic fairing methods for curves and surfaces. A classification is established and advantages and drawbacks of the methods are commented.
Vivo Lorenzo, Manuel   +1 more
openaire   +1 more source

Potential of Mobile LiDAR Sensors in Hiking Trail Management. [PDF]

open access: yesSensors (Basel)
Fernandes R   +3 more
europepmc   +1 more source

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