Results 161 to 170 of about 1,919,199 (295)

Survey on 3D Surface Reconstruction

Journal of Information Processing Systems, 2016
openaire   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Urban road surface crack detection based on U-net and ResNeXt network. [PDF]

PLoS One
Qiao J, Wang H, Zhou Z, Meng Y, Gong M.
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Seasonal Variation in Diatom Availability and Utilization by Juvenile Japanese Sea Cucumber <i>Apostichopus japonicus</i>. [PDF]

Microorganisms
Matsumoto T, Matsuno K, Anaguchi Y, Inaba N.   +3 more
europepmc   +1 more source

Surface Features, Missouri Geological Survey [PDF]

The American Naturalist, 1897
openaire   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Integration of ERT and Geotechnical Investigation for River Restoration: A Case Study of Dam Removal Site Characterization. [PDF]

Environ Manage
Rahimi M, Wood CM, Befus KM, Holt JJ, Thompson G, Fathizadeh M.   +5 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

An Ecosystem-Scale Model of PFAS Dynamics in Stream-to-Riparian Food Webs. [PDF]

Environ Sci Technol
Campbell KS, Wesner JS, Walters DM, Helton AM, Baranovic AM, Agrawal A, Stricker CA, Provatas AA, Kraus JM, Briggs MA, Brandt JE.   +10 more
europepmc   +1 more source