Results 171 to 180 of about 8,878,259 (313)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Freycinet Estuary, Western Australia [cartographic material].

open access: yes, 1942
1st ed. "Printed by A.H.Q. Cartographic Company 1942."; Catalogue record generated as part of a batch load.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map ...
Australia. Army. Survey Corps.
core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Simpson Desert, South Australia [cartographic material].

open access: yes, 1941
1st ed. "Printed by A.H.Q. Cartographic Company 1941."; Catalogue record generated as part of a batch load.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map ...
Australia. Army. Survey Corps.
core  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Birdum, Northern Territory [cartographic material].

open access: yes, 1943
Rev 2nd ed. "Drawn and Reproduced by L.H.Q. (Aust.) Cartographic Company. 1943."; Catalogue record generated as part of a batch load.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map ...
Australia. Army. Survey Corps.
core  

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