Results 51 to 60 of about 4,656,236 (296)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Water surface topology of supercritical junction flow

open access: yesJournal of Hydrology and Hydromechanics, 2019
The complexity of flow conditions at junctions amplifies significantly with supercritical flow. It is a pronounced three-dimensional two-phased flow phenomenon, where standing waves with non-stationary water surface are formed.
Rak Gašper   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Magnetic surface topology in decaying plasma knots

open access: yesNew Journal of Physics, 2017
Torus-knot solitons have recently been formulated as solutions to the ideal incompressible magnetohydrodynamics (MHD) equations. We investigate numerically how these fields evolve in resistive, compressible, and viscous MHD. We find that certain decaying
C B Smiet   +3 more
doaj   +1 more source

Partial proteolysis improves the identification of the extracellular segments of transmembrane proteins by surface biotinylation

open access: yesScientific Reports, 2020
Transmembrane proteins (TMP) play a crucial role in several physiological processes. Despite their importance and diversity, only a few TMP structures have been determined by high-resolution protein structure characterization methods so far.
Tamás Langó   +8 more
doaj   +1 more source

Meshing skin surfaces with certified topology [PDF]

open access: yesComputational Geometry, 2006
Skin surfaces form a class of tangent continuous surfaces defined in terms of a set of balls (the atoms of the molecule) and a shrink factor. They are used for the visualization of molecules and for approximation purposes. The authors present an algorithm that approximates a skin surface with a topologically correct mesh.
Nico Kruithof, Gert Vegter
openaire   +5 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

On the profinite rigidity of surface groups and surface words

open access: yesComptes Rendus. Mathématique, 2021
Surface groups are determined among limit groups by their profinite completions. As a corollary, the set of surface words in a free group is closed in the profinite topology.
Wilton, Henry
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

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