Results 51 to 60 of about 5,157,090 (300)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Methods for designing the next generation of aircraft architectures using topology optimisation [PDF]

open access: yes, 2010
The need from energy efficient transportation has resulted in a growing interest in new aircraft configurations such as the Blended Wing Body. There is very little collective knowledge on the optimal structural layouts of these aircraft, and the ...
Eves, Jamie Samantha
core   +4 more sources

Water surface topology of supercritical junction flow

open access: yesJournal of Hydrology and Hydromechanics, 2019
The complexity of flow conditions at junctions amplifies significantly with supercritical flow. It is a pronounced three-dimensional two-phased flow phenomenon, where standing waves with non-stationary water surface are formed.
Rak Gašper   +2 more
doaj   +1 more source

Topology optimization of engine bracket arm using BESO

open access: yesInternational Journal for Simulation and Multidisciplinary Design Optimization, 2023
An engine bracket is one of the most critical components of the engine used for mounting and supporting the engine in the vehicles. Today, the automobile industry requires lightweight components, which will reduce the car's overall weight when fitted ...
Srivastava Saurabh   +2 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Magnetic surface topology in decaying plasma knots

open access: yesNew Journal of Physics, 2017
Torus-knot solitons have recently been formulated as solutions to the ideal incompressible magnetohydrodynamics (MHD) equations. We investigate numerically how these fields evolve in resistive, compressible, and viscous MHD. We find that certain decaying
C B Smiet   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Partial proteolysis improves the identification of the extracellular segments of transmembrane proteins by surface biotinylation

open access: yesScientific Reports, 2020
Transmembrane proteins (TMP) play a crucial role in several physiological processes. Despite their importance and diversity, only a few TMP structures have been determined by high-resolution protein structure characterization methods so far.
Tamás Langó   +8 more
doaj   +1 more source

Multicritical Fermi Surface Topological Transitions [PDF]

open access: yesPhysical Review Letters, 2019
A wide variety of complex phases in quantum materials are driven by electron-electron interactions, which are enhanced through density of states peaks. A well known example occurs at van Hove singularities where the Fermi surface undergoes a topological transition.
Dmitry V. Efremov   +5 more
openaire   +6 more sources

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