Results 41 to 50 of about 2,202,413 (261)

Administering Blinatumomab via Continuous Intravenous Infusion in Pediatric Patients—A Single‐Institution Retrospective Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab, a CD19xCD3 bispecific T‐cell engager, has become standard therapy for children with de novo B‐cell acute lymphoblastic leukemia (B‐ALL). This retrospective review describes the experience of blinatumomab administration in pediatric patients.
Julia M. Hurley   +6 more
wiley   +1 more source

TiO2 coatings doped with MoS2 nanoparticles using plasma electrolytic oxidation on Ti–6Al–4V alloy: Application for enhanced and functional bio-implant surface

open access: yesJournal of Materials Research and Technology
The focus of this study was to examine the surface, mechanical, corrosion, and bioactive characteristics of TiO2 coatings doped with different grams of nanoparticles of MoS2, which were fabricated using the plasma electrolytic oxidation (PEO) technique ...
Sidra Sadaf Nisar, Han-Cheol Choe
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Influence of Surface Structure on Corrosion Behaviour of Welded Stainless Steel AISI 316l

open access: yesCommunications, 2014
The work deals with influence of surface structure on corrosion behaviour of austenitic stainless steel AISI 316L welded by TIG method without filler. Surfaces of the welded stainless steel were modified by mechanical treatment methods (grinding, garnet ...
Monika Halamova   +3 more
doaj   +1 more source

Optimized fatigue performance of martensitic stainless steel AISI 440C using deep rolling integrated into hardening process [PDF]

open access: yesJournal of Mining and Metallurgy. Section B: Metallurgy, 2018
The deep rolling process can be modified by annealing at appropriate temperature and time to optimize the fatigue performance of metallic materials.
Donhongprai P., Juijerm P.
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Comprehensive evaluation of MWCNT/HAp and Cu-functionalized MWCNT/HAp coatings on Ti6Al4V implants: Enhancing surface characteristics and biocompatibility via plasma electrolytic oxidation

open access: yesJournal of Materials Research and Technology
This study investigates the evolving relationships and interactions between two distinct materials used in hard tissue implants: multi-walled carbon nanotubes (MWCNTs) and copper nanoparticles (Cu NPs).
Mahendran Logesh   +2 more
doaj   +1 more source

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