Results 61 to 70 of about 13,213,284 (302)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
EFFECT OF SURFACE TREATMENT ON ENAMEL SURFACE ROUGHNESS
Journal of Istanbul University Faculty of Dentistry, 2016 To compare the effects of different methods of surface treatment on enamel roughness.Ninety human maxillary first premolars were randomly divided into three groups (n=30) according to type of enamel surface treatment: I, acid etching; II, Er:YAG laser; III, Nd:YAG laser.
Şeyda Erşahan +1 more
openaire +3 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Journal of Materials Research and TechnologyThis study investigates the evolving relationships and interactions between two distinct materials used in hard tissue implants: multi-walled carbon nanotubes (MWCNTs) and copper nanoparticles (Cu NPs).
Mahendran Logesh +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Effects of (NH4)2Sx Treatment on Surface Work Function and Roughness of Indium–tin-oxide
, 2013 [[abstract]]In this study, the effects of an (NH4)2Sx treatment on the surface work function (SWF) and roughness of indium–tin-oxide (ITO) have been investigated.
Lin, Yow-Jon; You, Chang-Feng; Tsai, Chia-Lung
core
Corrosion preserving high density plasma treatment of precipitation hardening stainless steel [PDF]
, 2018 Publisher Copyright: © 2017Specialty alloys such as precipitation hardening stainless steels are routinely used in critical applications requiring high strength and corrosion resistance, e.g.
Domínguez-Meister, Santiago +13 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Fatigue strength improvement of Mg alloy AZ61 by double ultrasonic shot peening
Nihon Kikai Gakkai ronbunshu, 2016 Rotary bending fatigue tests using magnesium alloy AZ61 treated by double ultrasonic shot peening (USP) and peening under other conditions were performed to investigate the effect of shot peening (SP) on the fatigue behavior and to obtain high and stable
Toshifumi KAKIUCHI +4 more
doaj +1 more source