Results 71 to 80 of about 13,213,284 (302)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Surface Functionalization of a Polyurethane Surface via Radio-Frequency Cold Plasma Treatment Using Different Gases

, 2020
Herein, the surface treatment of polyurethane (PU) films via air, O2, N2, Ar, and their mixtures were tested. The treatment was performed to incorporate new polar functionalities on the polymer surface and achieve improved hydrophilic characteristics ...
Salma Habib, Aya E. Abusrafa, Abusrafa, A.E., Anton Popelka, Popelka, A., Habib, S.   +5 more
core   +1 more source

Influence of Shot Peening on AlSi10Mg Parts Fabricated by Additive Manufacturing

Journal of Manufacturing and Materials Processing, 2018
The additive manufacturing (AM) of aluminum alloys promises to considerably enhance the performance of lightweight critical parts in various industrial applications.
Ahmed H. Maamoun, Mohamed A. Elbestawi, Stephen C. Veldhuis   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Microstructural Evolution within the Interphase between Hardening Overlay and Existing Concrete Substrates

Applied Sciences, 2017
This article presents the microstructural evolution within the interphase between a hardening overlay made of cement mortar and an existing concrete substrate.
Łukasz Sadowski, Damian Stefaniuk
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Plastic surface modification : surface treatment and adhesion /

, 2010
"The aim of this book is to describe the primary polymer adhesion issues faced by manufacturers, processors and converters, to outline a variety of methods for attaining an appropriately activated surface, and to provide the diagnostics for various ...
Wolf, Rory A.
core  

Laser Surface Treatment of a Polymeric Biomaterial: Wettability Characteristics and Osteoblast Cell Response Modulation

, 2014
Biotechnology has the potential to improve people's quality of life and holds the key to-many unmet clinical needs. In the UK alone the biotechnology market is worth £4.5 billion and estimates of future growth ranks from 10 to 15%.
Waugh, David G., Lawrence, Jonathan
core   +2 more sources

Performance assessment of carbon based on lignocellulosic material as an effective biosorbent for elimination of iron and manganese from monazite leachate

Scientific Reports
The purification of REEs from leaching liquor of monazite ore; which contains contaminated iron and manganese, are significant important for REEs applications.
G. E. Sharaf El-Deen, B. S. Girgis, S. E. A. Sharaf El-Deen   +2 more
doaj   +1 more source