Results 21 to 30 of about 1,775,266 (219)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Corrigendum to "Estimating water availability across the Upper Salween and Mekong river basins" [PDF]
No abstract available.
S. Liu +8 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Changing Flood‐Generating Mechanisms Impact Flood Characteristics in Snow‐Dominated Catchments
Global warming is shifting the characteristics of snowmelt floods, while simultaneously altering flood‐generating mechanisms in cold regions. Here, we disentangle the contributions of inter‐type mechanism transitions from intra‐type characteristic shifts
Xinli Bai +7 more
doaj +1 more source
Quantifying terminal-lake dynamics is crucial for understanding water-ecosystem-economy relationship across endorheic river basins in arid environments.
Bei Li +4 more
doaj +1 more source
Despite the fact that gross primary productivity (GPP) and water use efficiency (WUE) have been widely used as indicators to evaluate the water-carbon cycle, uncertainties exist in the patterns of GPP and WUE responses to climate variability along ...
Xiaoyang Li +4 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Strong Agricultural Resilience to 2022 Southern China Drought
Meteorological drought, especially when influenced by human activities, significantly impacts agriculture. We assessed the Yangtze River Basin (YRB)’s crop ecosystem resilience during the 2022 southern China drought.
Yijing Cao +7 more
doaj +1 more source
Increased Grain Crop Production Intensifies the Water Crisis in Northern China
Growing crop production increases agricultural water consumption (AWC), but whether these two factors are matched in northern and southern China in the past two decades remains controversial.
Xiaojie Li +8 more
doaj +1 more source

