Results 31 to 40 of about 92,151 (207)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Strong Agricultural Resilience to 2022 Southern China Drought
Meteorological drought, especially when influenced by human activities, significantly impacts agriculture. We assessed the Yangtze River Basin (YRB)’s crop ecosystem resilience during the 2022 southern China drought.
Yijing Cao +7 more
doaj +1 more source
Despite the fact that gross primary productivity (GPP) and water use efficiency (WUE) have been widely used as indicators to evaluate the water-carbon cycle, uncertainties exist in the patterns of GPP and WUE responses to climate variability along ...
Xiaoyang Li +4 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Changing Flood‐Generating Mechanisms Impact Flood Characteristics in Snow‐Dominated Catchments
Global warming is shifting the characteristics of snowmelt floods, while simultaneously altering flood‐generating mechanisms in cold regions. Here, we disentangle the contributions of inter‐type mechanism transitions from intra‐type characteristic shifts
Xinli Bai +7 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Direct vegetation response to recent CO2 rise shows limited effect on global streamflow
Global streamflow, crucial for ecology, agriculture, and human activities, can be influenced by elevated atmospheric CO2 (eCO2) though direct regulation of vegetation physiology and structure, which can either decrease or increase streamflow.
Haoshan Wei +6 more
doaj +1 more source
Quantifying terminal-lake dynamics is crucial for understanding water-ecosystem-economy relationship across endorheic river basins in arid environments.
Bei Li +4 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source

