Results 141 to 150 of about 247,498 (307)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Sea surface temperature trends in the coastal ocean [PDF]

, 2013
Sea surface temperature (SST) trends in the coastal zone are shown to be increasing at rates that exceed the global trends by up to an order of magnitude. This paper compiles some of the evidence of the trends published in the literature.
Al-Rashidi, Thamer B., Nicholls, R.J., Rakha, Karim, Amos, C.L., El-Gamily, Hamdy   +4 more
core  

Unveiling PFAS hazard in European surface waters using an interpretable machine-learning model

Environment International
Per- and polyfluoroalkyl substances (PFAS), commonly known as “forever chemicals”, are ubiquitous in surface waters and potentially threaten human health and ecosystems.
Li Zhao, Jian Chen, Jiaqi Wen, Yangjie Li, Yingjie Zhang, Qunyue Wu, Gang Yu   +6 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Implementation of a method to determine sub-nanomolar concentrations of iron in seawater and its application to the study of marine iron biogeochemistry at the ocean-shelf interface [PDF]

, 2006
The aim of this study was to improve our understanding of the marine iron cycle using a newly implemented technique to measure dissolved iron in seawater.
Nedelec, F., Nedelec, Florence
core  

Carbon Isotopic Composition in the Water Column of Lake Rotsee Reveals Importance of Methane Oxidation in Aquatic Environments

CHIMIA, 2012
Torsten Diem, Oliver Scheidegger, Carsten J. Schubert   +2 more
doaj   +1 more source

Specificity of Lessons of “Literature of the Native Land” in School

Journal of Danubian Studies and Research, 2017
In the article the attention is drawn to the topic of the specific nature of literature lessons of the native land and their implementation in the school.
Tetyana Byelobrova
doaj  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source