Results 51 to 60 of about 158,615 (263)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Sensors, 2023 A novel DAS setup based on geometric phases in coherent heterodyne detection is applied for the first time to the characterisation of the Earth’s subsurface.
Sabahat Shaheen +2 more
doaj +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
FEBS Open Bio, EarlyView.We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Polarization conversion with a photonic crystal slab [PDF]
Journal of the European Optical Society-Rapid Publications, 2008 We show that a photonic crystal slab can enable efficient polarization conversion. Two mechanisms are identified. The first mechanism relies on the anisotropy of the bulk properties of the metamaterial and is mediated by interferences.
Laroche Marine +3 more
doaj +1 more source
Impact of a Turbulent Ocean Surface on Laser Beam Propagation
Sensors, 2022 The roughness of the ocean surface significantly impacts air-to-sea imaging, oceanographic monitoring, and optical communication. Most current and previous methods for addressing this roughness and its impact on optical propagation are either entirely ...
Omar Alharbi, Tim Kane, Diane Henderson
doaj +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Relocation of Light and Moderate‐Magnitude (M4–6) Seismicity Along the Central Mid‐Atlantic
Geochemistry, Geophysics, Geosystems, 2018 We estimate precise relative epicentroid locations of earthquakes along the Mid‐Atlantic Ridge (MAR) between 12°N and 19°N using intermediate‐period Rayleigh and Love wave cross‐correlation measurements.
K. Michael Cleveland +2 more
doaj +1 more source
A Coherent on Receive X-Band Marine Radar for Ocean Observations
Sensors, 2021 Marine radars are increasingly popular for monitoring meteorological and oceanographic parameters such as ocean surface wind, waves and currents as well as bathymetry and shorelines.
Jochen Horstmann +5 more
doaj +1 more source