Results 61 to 70 of about 542,344 (303)

Will surface winds weaken in response to global warming?

Environmental Research Letters, 2016
The surface Walker and tropical tropospheric circulations have been inferred to slow down from historical observations and model projections, yet analysis of large-scale surface wind predictions is lacking.
Jian Ma, Gregory R Foltz, Brian J Soden, Gang Huang, Jie He, Changming Dong   +5 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Forecasting Cool Season Daily Peak Winds at Kennedy Space Center and Cape Canaveral Air Force Station [PDF]

, 2008
The expected peak wind speed for the day is an important element in the daily 24-Hour and Weekly Planning Forecasts issued by the 45th Weather Squadron (45 WS) for planning operations at Kennedy Space Center (KSC) and Cape Canaveral Air Force Station ...
Barrett, Joe, III, Roeder, William, Short, David   +2 more
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Impact of Station Relocation on Observed Surface Wind Measurement Data and Its Application Effectiveness

应用气象学报
Surface wind speed time series from national meteorological stations are frequently utilized in studies of wind climate change analysis, wind energy resource assessment, and engineering considerations for wind resistance.
Zhang Yongshan, Zhao Xiaodong, Yuan Chunhong, Song Lili   +3 more
doaj   +1 more source

Diurnal Variations in Surface Wind over the Tibetan Plateau

Atmosphere, 2019
This study uses hourly surface wind direction and wind speed observations from 53 meteorological stations on the Tibetan Plateau (TP) (70–105° E, 25–45° N) between 1995 and 2017 to investigate diurnal variations in the surface wind ...
Yufei Zhao, Jianping Li, Qiang Zhang, Xiaowei Jiang, Aixia Feng   +4 more
doaj   +1 more source

Decadal changes of the Western Arabian sea ecosystem [PDF]

, 2016
Historical data from oceanographic expeditions and remotely sensed data on outgoing longwave radiation, temperature, wind speed and ocean color in the western Arabian Sea (1950–2010) were used to investigate decadal trends in the physical and biochemical
AK Srivastava, B Liebmann, C Huang, DW Kim, DY Gong, DY Gong, ED Prince, F Panagiotopoulos, F Yao, Fishery Statistics Book, Fishery Statistics Book, HM Al-Gheilani, HR Gomes, II Zveryaev, JJ McCarthy, JM Morrison, JS Gray, K Banse, K Sherman, L O’Brien, L Resplandy, L Stramma, M Chierici, M Tomzac, MA Peňa, MA Sundermeyer, NH Saji, P Craven, PA Francis, PJ Durack, PJ Herring, R D’Arrigo, R Kistler, R Shinjo, R Snider, RT Barber, S Uddin, SA Piontkovski, SA Piontkovski, SA Piontkovski, SA Piontkovski, SC Doney, SJ Burns, TD Clayton, U Neff, U Von Rad, V Gouretski, VN Eremeev, WW Gregg   +48 more
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

On the Variability of Surface Tension with Mean Wind Speed

Journal of Physical Oceanography, 1977
Abstract In situ measurements of surface tension obtained by R.V. Gauss under coastal (North Sea of the Island of Sylt) and by R.V. Meteor under open sea conditions (GATE area) are Compared with time variations of the surface mean wind speed. The results indicate that the surface tension of the sea surface may attain values which are 21 dyn cm−1 below ...
Hühnerfuss, H., Walter, W., Kruspe, G.
openaire   +3 more sources