Results 41 to 50 of about 59,154 (224)

On the Moduli Space of Singular Euclidean Surfaces [PDF]

open access: yes, 2007
The goal of this paper is to develop some aspects of the deformation theory of piecewise flat structures on surfaces and use this theory to construct new geometric structures on the moduli space of Riemann surfaces.Comment: To appear in the Handbook of ...
Troyanov, Marc
core   +3 more sources

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

open access: yesAdvanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang   +12 more
wiley   +1 more source

Strong-field tidal distortions of rotating black holes: III. Embeddings in hyperbolic 3-space

open access: yes, 2017
In previous work, we developed tools for quantifying the tidal distortion of a black hole's event horizon due to an orbiting companion. These tools use techniques which require large mass ratios (companion mass $\mu$ much smaller than black hole mass $M$)
Hughes, Scott A.   +2 more
core   +1 more source

Bioenergy Cropping Reduces the Spatiotemporal Scaling of Soil Bacterial Biodiversity

open access: yesAdvanced Science, EarlyView.
Consistent with patterns observed in plant and animal communities, soil bacterial communities exhibit significant species–time–area and phylogenetic–time–area relationships independent of nested structure. Bioenergy cropping significantly reduces the spatiotemporal scaling rates, particularly in sandy loam soils.
Zhencheng Ye   +19 more
wiley   +1 more source

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

open access: yesAdvanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li   +10 more
wiley   +1 more source

Volume Growth, Number of Ends and the Topology of a Complete Submanifold

open access: yes, 2012
Given a complete isometric immersion $\phi: P^m \longrightarrow N^n$ in an ambient Riemannian manifold $N^n$ with a pole and with radial sectional curvatures bounded from above by the corresponding radial sectional curvatures of a radially symmetric ...
Gimeno, Vicent, Palmer, Vicente
core   +1 more source

Customizing Tactile Sensors via Machine Learning‐Driven Inverse Design

open access: yesAdvanced Science, EarlyView.
ABSTRACT Replicating the sophisticated sense of touch in artificial systems requires tactile sensors with precisely tailored properties. However, manually navigating the complex microstructure‐property relationship results in inefficient and suboptimal designs.
Baocheng Wang   +15 more
wiley   +1 more source

Flexible IMU Sensor Array For 3D Colonoscope Shape Reconstruction and AI‐Based Loop Detection

open access: yesAdvanced Science, EarlyView.
We propose a sensing platform for 3D visualization of the colonoscope combined with artificial intelligence (AI)‐based loop detection. The system consists of an array of 15 inertial measurement units (IMUs) mounted on a flexible printed circuit board that can be retrofitted into the instrument channel of conventional colonoscopes.
Tuukka Panula   +3 more
wiley   +1 more source

SDS‐CRISPR for Single‐Nucleotide Variant Detection

open access: yesAdvanced Science, EarlyView.
Structure‐disruption‐sensitive CRISPR (SDS‐CRISPR) converts structural instability into single‐nucleotide precision, thereby overcoming mismatch tolerance in canonical Cas12a and enabling versatile diagnostics across DNA, RNA, and microRNA targets. When applied to rapid IDH1 mutation detection for glioma genotyping and integrated with lateral‐flow ...
Xin Guan   +12 more
wiley   +1 more source

Physics‐Constrained Constitutive Learning of Rate‐Limiting Timescales for Efficient Hydrogen‐Based Direct Reduction for Green Steel Making

open access: yesAdvanced Science, EarlyView.
A conversion‐resolved constitutive framework is developed for the hydrogen‐based direct reduction of iron oxide pellets. Effective reaction and transport timescales are inferred directly from measured trajectories and mapped against operating conditions, pellet architecture, and composition. The analysis reveals how late‐stage transport control emerges
Anurag Bajpai   +3 more
wiley   +1 more source

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