Results 161 to 170 of about 11,710 (214)
Advanced Science, EarlyView.This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang +5 more
wiley +1 more source
Impact of Cutting Parameters and Tool Type on Surface Finish in MQL Turning of Inconel 625. [PDF]
Materials (Basel)Machno M, Zębala W, Franczyk E.
europepmc +1 more source
Advanced Science, EarlyView.AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie +14 more
wiley +1 more source
Targeting the RSV and hMPV L Protein: Cryo-EM and Structure-Based Approaches to Antiviral Drug Discovery. [PDF]
BiomoleculesPark YH, Kim R, Song KH, Jung HS.
europepmc +1 more source
Advanced Science, EarlyView.Leveraging the critical role of glutathione (GSH) in mediating drug resistance and scavenging reactive oxygen species (ROS) in cancer cells, a carrier‐free GSH‐consuming theranostic nanoprodrug, consisting of a BODIPY photosensitizer and the chemotherapeutic drug paclitaxel linked through a GSH‐consuming drug linker, is developed to deeply explore the ...
Hansheng Huang, Binglin Sui
wiley +1 more source
Atomistic Blueprinting of Electrochemical CO Reduction Reaction Pathways over Transition Metal Phosphides. [PDF]
MoleculesAwais M, Abghoui Y.
europepmc +1 more source
Macrophage Trogocytosis of Tumor Cells Drives the Immunosuppression of Tumor Microenvironment
Advanced Science, EarlyView.Trogocytosis efficiency varies significantly among different tumor cells and is inversely related to their cortical stiffness; this efficiency dictates the extent of immunosuppression via upregulation of CXCL5 and Arg‐1, ultimately driving CD8+T cell exhaustion and tumor escape.
Chao Liang +9 more
wiley +1 more source
Evaluating the Precision of 3D Morphological Reconstruction for Asphalt Pavement Textures via Close-Range Photogrammetry. [PDF]
Materials (Basel)Song L, Yun D, Wang L, Jiang S, Gao J.
europepmc +1 more source
Advanced Science, EarlyView.Engineered Escherichia coli Nissle 1917 with a tannic acid‐mediated BPA coating enables tumor‐targeted boron delivery for BNCT. The low‐level incidental radiation generated during BNCT activate a RecA‐driven circuit to induce CXCL10, while radiation‐enhanced bacterial colonization triggers in situ vaccination and systemic antitumor immunity.
Yang Liu +11 more
wiley +1 more source
Comprehensive Experimental Analysis of the Effect of Drilled Material on Torque Using Machine Learning Decision Trees. [PDF]
Materials (Basel)Hnátik J +6 more
europepmc +1 more source