Results 41 to 50 of about 265,481 (302)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Adsorption Kinetics of Polymer/Surfactant Mixtures at an Expanding Air/Water Interface [PDF]
, 2013 The dynamic adsorption mechanisms of a range of polymer/surfactant mixtures have been studied at the expanding air/water interface created by an overflowing cylinder.
ANGUS-SMYTH, ANNA
core
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Salt Effect on the Cloud Point Phenomenon of Amphiphilic Drug-Hydroxypropylmethyl Cellulose System
Journal of Chemistry, 2014 Effect of two amphiphilic drugs (tricyclic antidepressant, nortriptyline hydrochloride (NORT), and nonsteroidal anti-inflammatory drug, sodium salt of ibuprofen (IBF)) on the cloud point of biopolymer hydroxypropylmethyl cellulose (HPMC) was studied ...
Mohd. Sajid Ali +2 more
doaj +1 more source
Assessment of Salt and Acid Droplets Evaporations on the Corrosion Mechanism of Aluminum
International Journal of Electrochemical Science, 2015 An approach for new experimental set up for monitoring the corrosion rate of aluminum along with the contact angle, droplet volume loss and droplet height of a single droplet of NaCl, NH4SO4, H2SO4 and HNO3 solutions placed gently on aluminum surface was
Gamal A. EL-Mahdy +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
The Effect of Cosmetic Treatment and Gel Laser Therapy on the Improvement of Comedogenic Skin Type
Gels, 2023 Comedogenic skin care receives little attention compared to the care or treatment of more serious acne manifestations. Traditional therapies may have limited success with potential side effects.
Jana Pavlačková +5 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Surfactant-mediated biodegradation of polycyclic aromatic hydrocarbons
, 2009 Polycyclic aromatic hydrocarbons (PAHs) are toxic environmental pollutants that are known or suspected carcinogens or mutagens. Bioremediation has been used as a general way to eliminate them from the contaminated sites or aquifers, but their ...
Jing-Liang Li (1974193) +1 more
core +2 more sources
Evolution of Particle Characterization: Past, Present, and Future
KONA Powder and Particle JournalParticle characterization underpins a wide range of fields, including mineral processing, materials science, nanotechnology, pharmaceuticals, food processing, agriculture, and environmental applications, by providing essential information on particle ...
Vasanthakumar Balasubramanian +1 more
doaj +1 more source