Results 21 to 30 of about 183,339 (264)

Investigation of Vaned-Recessed Casing Treatment in a Low-Speed Axial Flow Compressor, Part I: Time-Averaged Results

open access: yesAerospace, 2023
This paper investigates the effects of two modifications to a vaned recessed casing treatment. First, the shape of a circular curve was used in the top of the treated casing. Second, a fully curved guide vane was also applied.
Mohammad Akhlaghi, Yahya Azizi
doaj   +1 more source

CREATION OF AFTERBURNING TURBOFAN ENGINE – HISTORY AND PRESENT

open access: yesАвіаційно-космічна техніка та технологія, 2020
The main problems of the creation of afterburning turbofan engines, among which the irremovable surge of the compressor, is disclosed by historical analysis.
Volodymyr Gerasimenko   +2 more
doaj   +1 more source

Polio Surge Capacity Support Program Contributions to Building Country Capacities in Support of Polio Outbreak Preparedness and Response: Lessons Learned and Remaining Challenges

open access: yesPathogens
Despite coordinated efforts at global level, through the Global Polio Eradication Initiative (GPEI), poliomyelitis disease (Polio) is still a major public health issue.
Fikru Abebe   +6 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Monsoon-Induced Surge during High Tides at the Southeast Coast of Vietnam: A Numerical Modeling Study

open access: yesGeosciences, 2019
In this study, monsoon-induced surge during high tides at the Southeast coast of Vietnam was analyzed based on the observed tide data at the Vung Tau station in the period between 1997—2016.
Nguyen Ba Thuy   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The aerodynamics of a blade pitch, rotor speed, and surge step for a wind turbine regarding dynamic inflow

open access: yesWind Energy, 2022
Floater motions introduce unsteadiness in the aerodynamics of floating offshore wind turbines. The aerodynamics of a wind turbine after three perturbations are studied: a blade pitch step, a rotor speed step for which dynamic inflow is expected, and a ...
Rémi Corniglion   +2 more
doaj   +1 more source

A Computational Method of Rotating Stall and Surge Transients in Axial Compressor

open access: yesEnergies, 2022
The onset of rotating stall and surge in compressors limits the operating range of aero-engines. Accurately predicting the key features during these events is critical in the engine design process.
Jiajia Ji, Jun Hu, Shuai Ma, Rong Xu
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

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