Results 241 to 250 of about 4,416 (303)

Programmed Cell Death in Cancer

open access: yesMedComm, Volume 6, Issue 9, September 2025.
Cancer is one of the most common and lethal diseases globally, with programmed cell death (PCD) playing a pivotal role in its pathogenesis and treatment. This comprehensive review covers the origin, developmental trajectory, and mechanisms of various PCDs, as well as their molecular connections with cancers. Latest studies have increasingly highlighted
Yuang Wei   +3 more
wiley   +1 more source

Transforming Growth Factor‐Beta Signaling in Cancer: Therapeutic Implications, Challenges, and Pathways to Progress

open access: yesMedComm – Oncology, Volume 4, Issue 3, September 2025.
TGF‐β inhibition is emerging as a promising cancer therapy, yet translating laboratory success to bedside implementation has suffered significant setbacks. The associated challenges include adverse drug reactions, inadequate predictive models, and activation of alternative signaling pathways.
Faizah A. Alabi   +5 more
wiley   +1 more source

Rare but relevant: Hydrocarbons and sudden sniffing syndrome

open access: yesAddiction, Volume 120, Issue 9, Page 1884-1888, September 2025.
Abstract Inhaled hydrocarbon‐associated sudden collapse (IHASC), often referred to as ‘sudden sniffing death syndrome’ is a critical and often fatal event linked to the inhalation of volatile hydrocarbons, primarily occurring in adolescents and young adults. This syndrome manifests as sudden cardiac and/or respiratory arrest, typically occurring during
Ingrid Berling   +1 more
wiley   +1 more source

Inherited Susceptibility to Cancer: Past, Present and Future

open access: yesAnnals of Human Genetics, Volume 89, Issue 5, Page 354-365, September 2025.
ABSTRACT Germline pathogenic variants (GPVs, ‘mutations’) causing inherited susceptibility to certain cancers (cancer susceptibility genes, CSGs) broadly belong to one of two main classes—loss of function variants in tumour suppressor genes (TSGs) or gain of function variants in proto‐oncogenes (an over‐simplification).
Shirley V. Hodgson   +3 more
wiley   +1 more source

Palaeohistology and life history of the early Palaeocene taeniodont Conoryctes comma (Mammalia: Eutheria)

open access: yesJournal of Anatomy, Volume 247, Issue 3-4, Page 819-841, September/October 2025.
Determining the life histories of mammals after the extinction of the dinosaurs is key to understanding why they rose so quickly to terrestrial dominance. This study analyses growth in a member of a key mammal group that traversed the extinction boundary.
Gregory F. Funston   +3 more
wiley   +1 more source

Development of a Low-Energy Mobile Current Waveform Impulse Generator for Application in Low Voltage Surge Arresters [PDF]

open access: diamond
Tiago Gonçalves Zacarias   +9 more
openalex   +1 more source

Resolving labour disputes in the Philippines: legitimacy and effectiveness in a polycentric regulatory framework

open access: yesJournal of Law and Society, Volume 52, Issue 3, Page 480-506, September 2025.
Abstract This article provides an empirically informed account of the processes for resolving labour disputes in the Philippines. Moving beyond earlier studies that have focused on the ineffectiveness of formal processes, we widen the scope of our inquiry to examine the labour dispute resolution regime as a polycentric regulatory framework. We focus on
CAROLYN SUTHERLAND   +1 more
wiley   +1 more source

Unpacking social media's role in sociopolitical development amidst the dual pandemics: Perspectives of marginalized adolescent organizers

open access: yesJournal of Research on Adolescence, Volume 35, Issue 3, September 2025.
Abstract “Dual pandemics” refers to the combination of COVID‐19 and structural racism in U.S. society—two forces that intersect to exacerbate inequities for marginalized and underrepresented communities. Today, we see marked differences in civic engagement for youth who were adolescents at the onset of the dual pandemics.
Angie Malorni, Sara Wilf
wiley   +1 more source

Cognitive loopholes of crime: Mapping the Codevelopment of moral disengagement within perceptions of risks and rewards

open access: yesJournal of Research on Adolescence, Volume 35, Issue 3, September 2025.
Abstract Prior research has examined individuals' perceptions of punishments (PP) and rewards (PR) for crime, as well as their use of moral disengagement (MD), to understand why adolescents and young adults commit crimes. However, the joint development of these cognitions as a broader risk‐perception mechanism remains understudied.
Romain Decrop   +8 more
wiley   +1 more source

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