Melanoma cell spheroid engraftment is optimized in the chicken chorioallantoic membrane overcoming the complexity of other in vivo models. Using this model, greater penetration of cerium oxide nanoparticles (nanoceria) functionalized with heparin in spheroids is observed via enhancement of vascularization than nanoceria alone.
Lu Fu+5 more
wiley +1 more source
Evolution of the reduction technique for unstable pelvic ring fractures: a narrative review. [PDF]
Shen L+6 more
europepmc +1 more source
Highly sprouting organoid‐like neurovascular spheroids (NVUs) are developed, featuring cell‐loaded poly‐3‐hydroxybutyrate 4‐hydroxybutyrate(P34HB) porous microsphere cores embedded within Gelatin Methacryloyl. NVUs formed complex vascular plexuses and secreted extracellular matrix in vitro, simulating autologous nerves and blood interaction.
Junjin Jie+5 more
wiley +1 more source
Accuracy of robot-assisted implant surgery versus freehand placement: a retrospective clinical study. [PDF]
Younis H+7 more
europepmc +1 more source
Nano‐Topography Enhanced Topological‐Cell‐Analysis in Radiation‐Therapy
Radiotherapy, a treatment that implies exposition of cells to radiation, offers promise to treat cancer. Here, it is hypothesized that the nanoscale details of a scaffold can amplify the response of cells to radiation, measured through topological variables, providing ways to assess the efficacy of Radiotherapy treatment.
Francesca Pagliari+8 more
wiley +1 more source
The Influence of Guiding Concept on the Accuracy of Static Computer-Assisted Implant Surgery in Partially Edentulous Cases: An In Vitro Study. [PDF]
Kasradze D, Kubilius R.
europepmc +1 more source
This study develops itaconate‐based polymer microparticles (IA‐MPs) for macrophage‐targeted intracellular delivery, overcoming the limitations of traditional itaconate administration. IA‐MPs achieve controlled release through phagocytosis, reducing pro‐inflammatory cytokine expression and reprogramming macrophage metabolism toward glycolysis.
Kaitlyn E. Woodworth+10 more
wiley +1 more source
Advancements and Challenges in Computer-Assisted Navigation for Cervical Spine Surgery: A Comprehensive Review of Perioperative Integration, Complications, and Emerging Technologies. [PDF]
Shahzad H+16 more
europepmc +1 more source
Mandibular Implants: A Metamaterial‐Based Approach to Reducing Stress Shielding
Metamaterial mandibular implants offer a novel approach to reducing stress shielding and enhancing biomechanical stimulation. This study compares a gyroid‐based metamaterial plate to a solid titanium plate using photoelasticity and finite element analysis.
Jorn‐Ids Heins+4 more
wiley +1 more source
Radiostereometric measurement of implant migration in robotically assisted vs conventional bi-cruciate stabilized cemented total knee arthroplasty: secondary analysis of a randomized controlled trial. [PDF]
Skåden Ø+7 more
europepmc +1 more source