Results 91 to 100 of about 4,600,529 (346)

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source

Outcome of open excisional breast biopsies in Abakaliki, South-East Nigeria

The Pan African Medical Journal, 2018
INTRODUCTION: open excisional breast biopsy is a known modality for treatment of breast lumps especially in developing countries. Other sophisticated methods are available for management of breast lumps in more advanced nations. Our aim in this study was
Maradona Ehikioya Isikhuemen, Monday Osaze Eliboh, Uche Emmanuel Eni, Kenneth Chinedu Ekwedigwe, Ileogben Sunday-Adeoye   +4 more
doaj   +1 more source

Vaginal evisceration as rare but a serious obstetric complication: A case series

Case Reports in Women's Health, 2016
Introduction: Gut prolapse through vagina is rare complication with only few cases reported in the literature. This article highlights untrained professionals induced obstetrical trauma as a cause of vaginal evisceration leading to serious but ...
Anadeep Chandi, Shaveta Jain, Sakshi Yadav, Jaiprakash Gurawalia   +3 more
doaj   +1 more source

Characterization and Prognosis of Biological Microenvironment in Lung Adenocarcinoma through a Disulfidptosis-Related lncRNAs Signature

Genetics Research, 2023
Background. The role of disulfidptosis-related lncRNAs remains unclear in lung adenocarcinoma. Methods. Analysis in R software was conducted using different R packages, which are based on the public data from The Cancer Genome Atlas (TCGA) database.
Zhuo Yang, Shenglan Cao, Fangli Wang, Kangming Du, Fang Hu   +4 more
doaj   +1 more source

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial‐Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C‐Dependent Stabilization of Snail mRNA

Advanced Science, EarlyView.
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao, Linlin Yang, Huanxiang Chen, Chenfeng Guo, Hongshen Lu, Ying Zhu, Xuanzhi Wang, Yang Li, Ruike Zhang, Zichong Huang, Yifang Chen, Keyu Jin, Zeduo Xu, Lingxiu Meng, Longfeng Zhang, Yuanyuan Han, Yicong Yan, Qiaozhen Kang, Junhu Wan, Hongyang Liu   +19 more
wiley   +1 more source

C-index: A novel method to assess surgical morbidity in obstetric and gynecological surgery: A retrospective study

Journal of Clinical Sciences
Background: There is a need to develop a method of assessing the outcomes of surgery that is as accurate as studying complications, more objective than patient-reported outcome measures and easier than cost-effective analysis.
Chanil Deshan Ekanayake, Arunasalam Pathmeswaran, Sakshara Ranasinghe, Amritha Sridaran, Yeshmitha Madanayake, Samurdika Nishamalee   +5 more
doaj   +1 more source

Obstetric Surgery for Perioperative Staff and Midwives

Journal of Perioperative Practice, 2009
Where a pregnant woman experiences trauma or has acute surgical needs there are additional concerns for the well being of both the woman and her foetus. This article explores obstetric procedures for the pregnant woman and discusses the implications for perioperative staff and midwives.
openaire   +3 more sources

The Experience of Women with Obstetric Fistula following Corrective Surgery: A Qualitative Study in Benadir and Mudug Regions, Somalia

Obstetrics and Gynecology International, 2018
Obstetric fistula is a severe maternal morbidity which can have devastating consequences for a woman's life and is generally associated with poor obstetric services leading to prolonged obstructed labour.
Adam A Mohamed, A. O. Ilesanmi, M. Dairo
semanticscholar   +1 more source

Medico-Legal Litigation : the clinical contractual nature of the Obstetric Anaesthetist-Patient relationship [PDF]

, 2014
Once the hand-maiden of obstetrics, obstetric anaesthesia, now a fully fledged sub-speciality today provides indispensable multi-faceted services mainly but not solely to the peripartum obstetric patient. Be it in routine as well as acute obstetric work,
Buttigieg, George Gregory, Buttigieg, Gabrielle   +1 more
core  

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source