Results 151 to 160 of about 1,013,460 (259)

Ubc9‐Mediated SUMOylation of RPL3, an Unappreciated Mechanism against Hepatocyte Senescence by Repressing the DHX9‐p16 Axis

Advanced Science, EarlyView.
Liver aging is characterized by a decline in the expression of the SUMO‐conjugating enzyme Ubc9, resulting in reduced SUMOylation levels in hepatocytes, particularly in the case of ribosomal protein RPL3. Disruption of RPL3 SUMOylation increases its nuclear translocation. Interestingly, ribosome‐free RPL3 facilitates the recruitment of helicase DHX9 to
Hao Xie, Zhichao Gao, Xin Liu, Shiyi Zhang, Yuhan Wang, Jia Gao, Ping Qi, Lu Zhang, Jiawei Zhao, Tian Xiong, Teng Huang, Jia Song, Qilin Yu, Shu Zhang, Yanjun Liu, Ping Yang, Maryam S. Al‐Motawa, Quan Gong, Junfeng Dong, Hao Yin, Fei Sun, Shiwei Liu, Cong‐Yi Wang   +22 more
wiley   +1 more source

Potential role of the comprehensive tooth extraction procedure in preventing medication related osteonecrosis of the jaw (MRONJ): a prospective cohort study. [PDF]

Orphanet J Rare Dis
Wang Y, Zhang Y, Li D, Zhang W, Wang S, Zheng X, Li Y, Deng T, Zong C, Tian L, Liu P, Xue Y.   +11 more
europepmc   +1 more source

Oral and Maxillofacial Surgery [PDF]

, 2016
井上 さやか, 今上 修一, 冨原 圭, 藤原 久美子, 野口 誠   +4 more
core   +1 more source

International Oral Surgery

Japanese Journal of Oral & Maxillofacial Surgery, 1976
openaire   +3 more sources

Uric Acid Functions as an Endogenous Modulator of Microglial Function and Amyloid Clearance in Alzheimer's Disease

Advanced Science, EarlyView.
Higher serum UA levels are associated with reduced AD risk in epidemiological studies. UA enhances microglial phagocytic capacity primarily by restoring CD36 and TREM2 receptor recycling that is impaired by Aβ exposure. Therapeutically, UA supplementation improves cognitive function and reduces neuropathology in AD mouse model by enhancing microglial ...
De Xie, Qiuyang Zheng, Jiaming Lv, Qian Zhang, Zhiwei Cui, Shuai Huang, Wei Yu, Binyang Chen, Wanling Que, Shanpan Fu, Yuemei Xi, Jiayu Chen, Xueling Ye, Shuyi Chen, Hairong Zhao, Tetsuya Yamamoto, Hidenori Koyama, Xin Wang, Jidong Cheng   +18 more
wiley   +1 more source

Optimizing Preoperative Anemia in Non-Metastatic Colorectal Cancer: A Systematic Review on Surgical Recovery and Outcomes. [PDF]

Cancers (Basel)
Tsokkou S, Konstantinidis I, Papakonstantinou M, Chatzikomnitsa P, Gkaitatzi AD, Liampou E, Fantakis A, Kolympa G, Toutziari E, Alexandrou D, Giakoustidis D, Bangeas P, Papadopoulos VN, Giakoustidis A.   +13 more
europepmc   +1 more source

Temporal Stretch‐Induced Nuclear Mechanosensing Coordinates Early Chromatin Accessibility and Genome Protection

Advanced Science, EarlyView.
Cyclic stretching of fibroblasts triggers coordinated nuclear mechanosensing events, including calcium ion release, perinuclear actin assembly, emerin translocation, and H3K9me3 loss, increasing chromatin accessibility for specific genes related to mechanotransduction and repair.
Hye‐Won Shim, Ji‐Young Yoon, Hwalim Lee, Shanika Karunasagara, Cheng Ji Li, Yongdae Shin, Sukbum Hong, Dong‐Joon Lee, Jung‐Hwan Lee, Kam W. Leong, Hae‐Won Kim   +10 more
wiley   +1 more source

Clinical outcomes in elderly patients on direct oral anticoagulant drugs undergoing surgery for acute hip fracture (AHF). [PDF]

Eur J Trauma Emerg Surg
Wemmert E, Eklöf P, Linder V, Rydberg EM, Dalla K, Nellgård B, Hessulf F, Piasecki A.   +7 more
europepmc   +1 more source

Novel Vascularized Human Liver Organoids for Modeling Alcohol‐Induced Liver Injury and Developing Hepatoprotective Therapy

Advanced Science, EarlyView.
This study successfully engineered vascularized liver organoids (3HLOs) by co‐culturing human reprogrammed hepatocyte‐like cells (hrHLs) with human umbilical vein endothelial cells (HUVECs) and human umbilical mesenchymal stem cells (HUMSCs). Upon implantation, the 3HLOs established functional vascular anastomosis with the host circulation and ...
Kangdi Yang, Xiayan Chu, Xuerui Wang, Wenkun Zhang, Jinnuo Lu, Chuting Xu, Shoucheng Hu, Guoyu Pan, Chih‐Tsung Yang, Xiaohui Zhang, Shaojin Li, Zhaobin Guo, Hanyang Liu, Guangbo Ge   +13 more
wiley   +1 more source

Effect of preoperative oral carbohydrate combined with postoperative early enteral nutrition on the perioperative rehabilitation of patients with colorectal cancer: a multicenter randomized controlled trial. [PDF]

Front Nutr
He Z, Liu Y, Xu Q, Yang X, Zhou D, Zhang L.   +5 more
europepmc   +1 more source