Results 41 to 50 of about 972,641 (271)

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

A semi-automatic computer-aided method for surgical template design [PDF]

open access: yesScientific Reports 6, Article number: 20280, 2016, 2016
This paper presents a generalized integrated framework of semi-automatic surgical template design. Several algorithms were implemented including the mesh segmentation, offset surface generation, collision detection, ruled surface generation, etc., and a special software named TemDesigner was developed.
arxiv   +1 more source

Estudo comparativo entre dois protocolos anestésicos envolvendo bloqueio do nervo alveolar inferior convencional e de Vazirani-Akinosi para exodontia de terceiro molar inferior

open access: yesRevista de Odontologia da UNESP
INTRODUÇÃO: O bloqueio do nervo alveolar inferior (BNAI) apresenta alta porcentagem de falha na Odontologia. A fim de melhorar esse índice, vêm-se estudando diferentes alternativas, como diferentes técnicas e soluções anestésicas.
Danilo de Paula Ribeiro Borges   +5 more
doaj   +1 more source

Metastatic Uterine Leiomyosarcoma in the Upper Buccal Gingiva Misdiagnosed as an Epulis [PDF]

open access: yes, 2014
Uterine leiomyosarcoma (LMS) is a rare tumor constituting 1% of all uterine malignancies. This sarcoma demonstrates an aggressive growth pattern with an high rate of recurrence with hematologic dissemination; the most common sites are lung, liver, and ...
Alesini F   +10 more
core   +2 more sources

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

open access: yesMolecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

Oral-3D: Reconstructing the 3D Bone Structure of Oral Cavity from 2D Panoramic X-ray [PDF]

open access: yesarXiv, 2020
Panoramic X-ray (PX) provides a 2D picture of the patient's mouth in a panoramic view to help dentists observe the invisible disease inside the gum. However, it provides limited 2D information compared with cone-beam computed tomography (CBCT), another dental imaging method that generates a 3D picture of the oral cavity but with more radiation dose and
arxiv  

Exodontia under anesthesia in patients with infantile cerebral palsy

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Dental assistance to patients with disabilities and comorbidities is a point of attention to their needs for a better quality of life. The treatment to patients with infantile cerebral palsy is a challenge for both the dentist and the anesthesiologist ...
Karell Piñón-García   +2 more
doaj  

Long-Term Follow-Up of SAPHO Syndrome for 15 Years Led to a Diagnosis of Temporomandibular Joint Pain and Trismus

open access: yesCase Reports in Dentistry, 2021
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a systemic disease with symptoms of pustular skin disease and sterile osteoarticular lesions. This disease rarely involves the temporomandibular joint (TMJ).
Koki Takamatsu   +5 more
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

OralViewer: 3D Demonstration of Dental Surgeries for Patient Education with Oral Cavity Reconstruction from a 2D Panoramic X-ray [PDF]

open access: yesarXiv, 2020
Patient's understanding on forthcoming dental surgeries is required by patient-centered care and helps reduce fear and anxiety. Due to the gap of expertise between patients and dentists, conventional techniques of patient education are usually not effective for explaining surgical steps.
arxiv  

Home - About - Disclaimer - Privacy