Results 81 to 90 of about 4,698,710 (369)

A coiled‐coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor

FEBS Letters, EarlyView.
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston, Jérôme Feuillard, Aurélie Ancelin, Joséphine Lai‐Kee‐Him, Konstantin Brodolin, Christian Chalut, Pontus Gourdon, Mickaël Blaise   +7 more
wiley   +1 more source

Early results of surgical and Endovascular intervention procedures in Lower extremity arterial disease [PDF]

Perspectives In Medical Research, 2020
Objective : To assess the early results of surgical and endovascular intervention in peripheral arterial disease Materials and methods : Retrospectively, we analysed the early results of treatment of lower extremity arterial diseases, managed at our ...
Sistla VPL Chandrakumar1 , Ajit Kumar Padhy2 , Sartaj Ahmed Guroo1 , Khushwant Popli2 , Madhur Kumar1 , Puneet Garg2 , Anubhav Gupta3
doaj  

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

Molecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens, Anouk Mentink, Frank A. W. Coumans, Eshwari Dathathri, Khrystany T. Isebia, Jaco Kraan, Ronald de Wit, John W. M. Martens, Leon W. M. M. Terstappen   +8 more
wiley   +1 more source

Transcatheter versus surgical closure of atrial septal defect: Comparison of early result and complication [PDF]

Romanian Journal of Pediatrics
Background. Surgical therapy for closure of atrial septal defect with cardiopulmonary bypass is the gold standard. Transcatheter closure has become an alternative for the treatment of atrial septal defect because 80-90% of atrial septal defects can be ...
Yayu Dwinita Jasin, Mahrus A. Rahman
doaj   +1 more source

Perspectives on Surgical Data Science [PDF]

arXiv, 2016
The availability of large amounts of data together with advances in analytical techniques afford an opportunity to address difficult challenges in ensuring that healthcare is safe, effective, efficient, patient-centered, equitable, and timely. Surgical care and training stand to tremendously gain through surgical data science.
arxiv  

Tool Detection and Operative Skill Assessment in Surgical Videos Using Region-Based Convolutional Neural Networks [PDF]

IEEE Workshop/Winter Conference on Applications of Computer Vision, 2018
Five billion people in the world lack access to quality surgical care. Surgeon skill varies dramatically, and many surgical patients suffer complications and avoidable harm.
Amy Jin, Serena Yeung, J. Jopling, J. Krause, D. Azagury, A. Milstein, Li Fei-Fei   +6 more
semanticscholar   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

RESULTS OF SURGICAL TECHNIQUES APPLIED IN BLEPHAROPTOSIS

Sanamed, 2019
Objective: Our aim was to analyze the success rates of patients who underwent levator aponeurosis or frontal suspension with silicone tube surgery due to blepharoptosis according to the elevator function (LF) and to compare our results with the ...
Ozturk Yucel, Ayyildiz Taha, Ozgur Rodop Ozlen, Oral Yesim, Kocabas Seyhan   +4 more
doaj   +1 more source

Prolonged Operative Duration Increases Risk of Surgical Site Infections: A Systematic Review

Surgical Infections, 2017
Background: The incidence of surgical site infection (SSI) across surgical procedures, specialties, and conditions is reported to vary from 0.1% to 50%.
Hang Cheng, B. P. Chen, I. Soleas, N. Ferko, C. Cameron, P. Hinoul   +5 more
semanticscholar   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source