Results 101 to 110 of about 5,970,578 (344)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Web-based modelling with applications to surgical training [PDF]
, 2002 Web-based surgical training has the potential to offer a cheap training platform, accessible from anywhere in the world, at any time. However the use of web-based VR for training faces a number of challenges including fast collision detection and real ...
Li, Ying
core +4 more sources
Surgical management for upper urinary tract transitional cell carcinoma [PDF]
, 2011 Background Upper tract transitional cell carcinomas (TCC) are uncommon and aggressive tumours. There are a number of surgical approaches to manage this condition including open radical nephroureterectomy and laparoscopic procedures.
El-Mokadem, Ismail +11 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Clinical OphthalmologyTahm Spitznagel,1,2 Gábor Márk Somfai,1– 3 Ferhat Turgut,1– 4 Paul Kang,5 Toam Katz,6,7 Sophie-Christin Kornelia Ernst,1,2,8 Ute Hornberger,1,2 Matthias Dieter Becker,1,2,9 Florian Heussen,10 Michaela Ramsauer1,2 1Department of Ophthalmology, Stadtspital
Spitznagel T +9 more
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Kenya Surgical Capacity Study: An Audit of Surgical Equipment/Infrastructure in Level 4 Public Hospitals [PDF]
Background: Access to surgical equipment is critical to providing safe and equitable operative care. This is the first nationwide study to provide data on the availability of surgical equipment in Kenya. Methods: This cross-sectional study collected data
Mariam Saad +9 more
core +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Prolonged Operative Duration Increases Risk of Surgical Site Infections: A Systematic Review
Surgical Infections, 2017 Background: The incidence of surgical site infection (SSI) across surgical procedures, specialties, and conditions is reported to vary from 0.1% to 50%.
Hang Cheng +5 more
semanticscholar +1 more source