Results 81 to 90 of about 4,146,169 (358)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Use of National Early Warning Score for observation for increased risk for clinical deterioration during post-ICU care at a surgical ward

open access: yesTherapeutics and Clinical Risk Management, 2019
Pia Katrin Klepstad,1 Trond Nordseth,2,3 Normunds Sikora,4 Pål Klepstad2,5 1Faculty of Medicine, Riga Stradins University, Riga, Latvia; 2Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University ...
Klepstad PK   +3 more
doaj  

The patient, case, individual and environmental factors that impact on the surgical count process: An integrative review

open access: yesJournal of Perioperative Nursing, 2019
Problem identification: The surgical count is an integral component of the perioperative nurse’s role designed to reduce the risk of unintentional retained items (URIs) during surgery.
Vicky Warwick   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Posterior Capsule Rupture and Vitreous Loss in Cataract Surgery: A Retrospective Analysis from a Swiss Tertiary Center

open access: yesClinical Ophthalmology
Tahm Spitznagel,1,2 Gábor Márk Somfai,1– 3 Ferhat Turgut,1– 4 Paul Kang,5 Toam Katz,6,7 Sophie-Christin Kornelia Ernst,1,2,8 Ute Hornberger,1,2 Matthias Dieter Becker,1,2,9 Florian Heussen,10 Michaela Ramsauer1,2 1Department of Ophthalmology, Stadtspital
Spitznagel T   +9 more
doaj  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Preventing and treating surgical site infection in patients with spinal metastatic disease [PDF]

open access: yes, 2013
Surgery to remove secondary spinal tumours is often necessary to relieve symptoms associated with metastatic spinal cord compression (MSCC). However, such individuals are at high risk of surgical site infection (SSI).
Lui, Steve   +3 more
core  

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