Results 121 to 130 of about 6,742,024 (351)

Efeitos da bromoprida na cicatrização de anastomoses no cólon esquerdo de ratos

open access: yesRevista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Avaliar os efeitos da bromoprida sobre a formação de aderências e a cicatrização de anastomoses de cólon esquerdo de ratos. MÉTODOS: Foram incluídos 40 ratos, divididos em dois grupos contendo 20 animais, para administração de bromoprida (grupo
Silvana Marques e Silva   +5 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Understanding effective management of postoperative wounds [PDF]

open access: yes, 2013
Acute surgical wounds generally heal with no problems. However, some wounds blister around the periwound area and surgical site infection postoperatively, partly due to inappropriate choice of wound dressing.
Ousey, Karen, Roberts, Peter
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Recent Residency Program Graduate Pledges Ongoing Support [PDF]

open access: yes, 2013
After graduating from Jefferson’s surgical residency program in 2008, Negar Golesorkhi, MD, went on to complete a prestigious breast surgical oncology fellowship at Allegheny Medical Center.

core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The role of magnetic resonance imaging in carpal tunnel syndrome: Correlation of clinical electrodiagnostic and intraoperative findings and staging

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
Objectives: A prospective, single-blind study was planned to investigate the role of magnetic resonance imaging (MRI) in the diagnosis, treatment, and staging of carpal tunnel syndrome (CTS).\r\nMethods: The study group was comprised of 43 hands of 25 ...
A. Erdem Bagatur, Gazi Zorer, Birol Oral
doaj  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

The effect of tourniquet use in total knee prosthesis

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
Objectives: The effects of tourniquet use were evaluated with regard to blood loss and rehabilitation in patients undergoing total knee prosthesis (TKP).\r\nMethods: Thirty-two consecutive patients with osteoarthritis were prospectively divided into two ...
Omer F. Bilgen, Yavuz Yilmaz
doaj  

Home - About - Disclaimer - Privacy