Results 131 to 140 of about 6,742,024 (351)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Acta Orthopaedica et Traumatologica Turcica, 2021 Objectives: This study was designed to evaluate the frequency of soft tissue lesions in intra-articular fractures of the distal end of the radius and their effects on functional outcome.
Mustafa Ozkan +4 more
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Surgical Control of Behavior [PDF]
, 1974 Dr. Kanoti is an associate professor of Christian Ethics at John Carroll University, Cleveland, Ohio. He has published numerous articles on ethical topics, moral theology and psychology.
Kanoti, George A.
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
PECULIARITIES OF SURGICAL TREATMENT OF BENIGN FORMATION OF MAMMARY GLAND
Актуальні проблеми сучасної медицини, 2019 The effectiveness of the use of remote surgical approaches in patients with benign formation of mammary gland was studied in this paper,. Before surgery, all patients underwent a standard set of instrumental examinations: mammography, ultrasound ...
Vitalii Makarov
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Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients.
New England Journal of Medicine, 2016 M. Leon +33 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
From Incision to Immunity: Integrating Surgery and Immunotherapy in Non-Small Cell Lung Cancer
ImmunoLung cancer is the most common cause of death due to cancer in the world, and non-small cell lung cancer (NSCLC) is the most common form of lung cancer, representing approximately 84% of all cases.
Michael J. Janes +5 more
doaj +1 more source