Results 61 to 70 of about 1,813,644 (300)

Sex discrepancies in pathophysiology, presentation, treatment, and outcomes of severe aortic stenosis

Frontiers in Cardiovascular Medicine, 2023
This review gives an overview of sex-based differences in aortic valve stenosis, spanning from pathophysiological mechanisms and disease progression, clinical presentation, presence of comorbidities, and diagnostic assessment, to treatment and outcomes ...
Julia Stehli, Sarah Zaman, Sarah Zaman, Barbara E. Stähli, Barbara E. Stähli   +4 more
doaj   +1 more source

Transcatheter-based aortic valve replacement vs. isolated surgical aortic valve replacement in 2020

Clinical Research in Cardiology, 2022
Based on the results of several recent randomized trials, European and American guidelines on valvular heart disease management have substantially expanded the indications for transcatheter aortic valve implantation (TAVI). We present an all-comer data on peri-operative risk profile and in-hospital outcomes from Germany for patients treated by TAVI or ...
Luise Gaede, Johannes Blumenstein, Clemens Eckel, Christina Grothusen, Vedat Tiyerili, Dagmar Sötemann, Holger Nef, Albrecht Elsässer, Stephan Achenbach, Helge Möllmann   +9 more
openaire   +2 more sources

Recent developments for surgical aortic valve replacement: the concept of sutureless valve technology [PDF]

, 2013
Aortic stenosis has become the most frequent type of valvular heart disease in Europe and North America and presents in the large majority of patients as calcified aortic stenosis in adults of advanced age.
Englberger, Lars, Carrel, Thierry, Stalder, Mario   +2 more
core   +2 more sources

Systematic Cardiac Phenotyping of Patients With Copy Number Variants in the 15q11.2 Breakpoint 1 to Breakpoint 2 Region: A Retrospective Cohort Study From Nine Pediatric Cardiac Centers

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Microdeletions impacting 15q11.2 breakpoint (BP) 1 to BP2, adjacent to the Prader–Willi critical region, have previously described neuropsychiatric associations, with potential low penetrance presentations of congenital heart disease (CHD) also identified.
Morgan B. Wright, Maria B. Padua, Lindsey R. Helvaty, Kim L. McBride, Gabrielle Geddes, Vidu Garg, Seema R. Lalani, Stephanie Burns Wechsler, Jennelle C. Hodge, Benjamin J. Landis, Stephanie M. Ware   +10 more
wiley   +1 more source

Longitudinal Echocardiographic Surveillance of Aortic Dilation in a Phenotype‐Enriched Turner Syndrome Cohort

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Turner syndrome (TS) is associated with thoracic aortopathy and increased risk for aortic dissection, yet the natural history of aortic dilation is not well understood. We performed a retrospective longitudinal study of individuals with TS who participated in the TS Society of the United States Healthy Heart Project between 2003 and 2023 ...
Dylan Doerner, Matthew R. Johnson, Sara Mansoorshahi, Rakesh Kathiresan, Katelyn Abel, Jonathan G. You, Emilio Quezada, Siddharth K. Prakash   +7 more
wiley   +1 more source

Intermediate‐Term Risk of Stroke Following Cardiac Procedures in a Nationally Representative Data Set

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundStudies on stroke risk following cardiac procedures addressed only perioperative and long‐term risk following limited higher‐risk procedures, were poorly generalizable, and often failed to stratify by stroke type.
Laura Stein, Alison Thaler, John W. Liang, Stanley Tuhrim, Amit S. Dhamoon, Mandip S. Dhamoon   +5 more
doaj   +1 more source

Immediate results of combined coronary bypass surgery and aortic valve replacement with incomplete and complete myocardial revascularization

Вестник хирургии имени И.И. Грекова, 2023
Introduction. Coronary heart disease and aortic valve stenosis still occupy a leading position among cardiovascular diseases. Against the background of an increase in life expectancy, patients with a combined pathology of the heart are increasingly ...
V. S. Litus, D. G. Gramatikov
doaj   +1 more source

Trends in Isolated Surgical Aortic Valve Replacement

JACC: Cardiovascular Interventions, 2019
We read with interest the paper by Kundi et al. [(1)][1] that assessed trends in transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) volume, and the effect of TAVR volume on SAVR mortality.
Paula D, Strassle, Sameer, Arora, John P, Vavalle   +2 more
openaire   +2 more sources

Therapy for Myhre Syndrome: Goals, Misconceptions, and Current Agents

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre Syndrome (MYHRS, MIM #139210) is a rare, multisystem connective tissue disorder caused by recurrent heterozygous gain‐of‐function pathogenic variants in the SMAD4 gene, a key player in TGF‐β signaling and a regulator of extracellular matrix homeostasis.
Alessandro De Falco, Alfonso Manuel D'Alessio, Nicola Brunetti‐Pierri   +2 more
wiley   +1 more source

TAVR and SAVR: Current Treatment of Aortic Stenosis

Clinical Medicine Insights: Cardiology, 2012
Transcatheter aortic valve replacement (TAVR) was approved in the United States in late 2011, providing a critically needed alternative therapy for patients with severe aortic stenosis previously refused surgical aortic valve replacement (SAVR).
P. Hu Patrick MD, Phd, FACC, FSCAI, FSVM
doaj   +1 more source