Results 161 to 170 of about 16,460 (246)
Advanced Healthcare Materials, Volume 15, Issue 26, 10 July 2026.A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni +7 more
wiley +1 more source
Advanced Science, Volume 13, Issue 39, 13 July 2026.Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang +11 more
wiley +1 more source
Use of Meloxicam or Ketoprofen for Piglet Pain Control Following Surgical Castration. [PDF]
Front Vet Sci, 2018 Viscardi AV, Turner PV.
europepmc +1 more source
Surgical or irradiation castration for patients with advanced breast cancer [PDF]
Cancer, 1969 openaire +2 more sources
Advanced Science, Volume 13, Issue 37, 3 July 2026.This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu +18 more
wiley +1 more source
The age of surgical castration affects the healing process in beef calves. [PDF]
Transl Anim Sci, 2017 Norring M, Mintline EM, Tucker CB.
europepmc +1 more source
Advanced Science, Volume 13, Issue 38, 9 July 2026.A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo +13 more
wiley +1 more source
Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies
Advanced Science, Volume 13, Issue 38, 9 July 2026.In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang +4 more
wiley +1 more source
BJUI Compass, Volume 7, Issue 7, July 2026.Abstract Objective The objective of this study is to examine whether a baseline calculation of PSAD is associated with prostate cancer‐specific mortality after 30 years of follow‐up. Methods One‐thousand seven‐hundred and seventy‐nine men were screened for prostate cancer with a PSA test, digital rectal exam (DRE) and ultrasound of the prostate (TRUS).
Sara Saliba +6 more
wiley +1 more source
Cancer, Volume 132, Issue 13, 1 July 2026.Abstract Background The combination of olaparib plus radium‐223 improved progression‐free survival in patients with metastatic castration‐resistant prostate cancer with bone metastases (BM) in the multicenter, randomized, phase 2 COMRADE trial (NCT03317391). Here, the patient‐reported outcome (PRO) analysis of this trial is reported.
Rana R. McKay +11 more
wiley +1 more source