Results 121 to 130 of about 4,264,300 (376)

589 Reducing Single-Use Surgical Instruments During Laparoscopic Appendicectomy: Using Sustainable Quality Improvement as a Catalyst to Encourage Wider Behavioural Change in a Surgical Department [PDF]

, 2022
Bryony Ford, Peter Labib, Aditya Kanwar, Grant Sanders, Walter Douie, Michelle Winfield   +5 more
openalex   +1 more source

Flexible Instruments for Endovascular Interventions: Improved Magnetic Steering, Actuation, and Image-Guided Surgical Instruments

IEEE robotics & automation magazine, 2018
Endovascular surgery has gained broad acceptance in the last few years. The current practice of endovascular procedures is limited by factors including patient-specific operation requirements, high-risk surgery procedures, and time-consuming operations ...
C. Heunis, J. Sikorski, S. Misra
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

A Novel Patient-Specific Human Cardiovascular System Phantom (HCSP) for Reconstructions of Pulsatile Blood Hemodynamic Inside Abdominal Aortic Aneurysm

IEEE Access, 2018
Background and objectives: Post-operative complications of endovascular aneurysm repair, such as endoleaks, migration, or angular bands in a stent-graft or narrowing and occlusion of a stent-graft lumen are potentially life-threatening and difficult to ...
Andrzej Polanczyk, Michal Podgorski, Maciej Polanczyk, Aleksandra Piechota-Polanczyk, Christoph Neumayer, Ludomir Stefanczyk   +5 more
doaj   +1 more source

A Kinematics Method Based on Dynamic Visual Navigation for the Instrument Arm of Surgical Robot [PDF]

, 2013
Lingtao Yu, Zhengyu Wang, Peng Yu, Tao Wang, Huajian Song   +4 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Thoracoscopic instruments do not interfere in the outcome of uncomplicated, experimental, video-assisted pulmonary lobectomy

Revista do Colégio Brasileiro de Cirurgiões
Objective: Since its first report, video-assisted thoracic surgery (VATS) lung lobectomy was carried out with the use of conventional surgical instruments, used in laparoscopy and open thoracotomy.
LEONARDO CESAR SILVA OLIVEIRA, JOSUE VIANA CASTRO   +1 more
doaj   +1 more source

The Diagnostic Efficiency of the Use of Non-Standard Surgical Instruments in Mediastinoscopy

, 2022
Kemal Karapınar, Merve Özbek, Yunus Seyrek, Cemal Aker, Ali Murat Akçıl, Levent Cansever, Mehmet Ali Bedirhan   +6 more
openalex   +1 more source