Results 51 to 60 of about 2,333,734 (298)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Background: Breast cancer is one of the most common malignancies worldwide, with significant implications for patient quality of life (QoL). As survival rates improve, assessing the long-term effects of treatment has become crucial.
Nazgul Dzhantemirova +4 more
doaj +1 more source
Identification of Surgical Instruments Using a Low Frequency Magnetic Field
Background: As part of a open surgical intervention, it is desirable to identify, track and count the surgical instruments used, in order to document and potentially optimize the process.
Ibrahim Ibrahim +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Research of personal surgical instruments for hip implant positioning. [PDF]
In this work, was performed the analysis of scientific literature, describes the types of personalized surgical instruments were, fields of application, functions performed.
Žagrakalis, Tomas,
core +1 more source
Functional surfaces of medical devices based on laser processing: a review
The preparation of functional surfaces is one of the important methods to enhance the therapeutic performance and safety of medical devices. Currently, the fabrication of functional surface microstructures based on laser processing is widely used in the ...
Xinhao DU +5 more
doaj +3 more sources
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
El objetivo principal de este trabajo es establecer una normativa, hasta ahora inexistente, que asegure la máxima calidad en la prestación de cuidados al paciente que debe someterse a cirugía.
E. Gómez Ávila, R. Ruiz López
doaj +1 more source
A novel olecranon-type tracheotomy and expansion forceps for single-person emergency airway access
BackgroundWe developed olecranon-type tracheotomy and expansion forceps (OTEF) for emergency tracheotomy in patients experiencing acute airway obstruction.
Liang Zhu +8 more
doaj +1 more source

