Results 61 to 70 of about 2,333,734 (298)

Interventions to reduce the risk of surgically transmitted Creutzfeldt–Jakob disease: a cost-effective modelling review

open access: yesHealth Technology Assessment, 2020
Background: Creutzfeldt–Jakob disease is a fatal neurological disease caused by abnormal infectious proteins called prions. Prions that are present on surgical instruments cannot be completely deactivated; therefore, patients who are subsequently ...
Matt Stevenson   +5 more
doaj   +1 more source

Endotoxins in surgical instruments of hip arthroplasty [PDF]

open access: yes, 2016
OBJECTIVE To investigate endotoxins in sterilized surgical instruments used in hip arthroplasties. METHOD A descriptive exploratory study conducted in a public teaching hospital. Six types of surgical instruments were selected, namely: acetabulum rasp,
Flavia Falci Ercole   +16 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Inspecting and unbending surgical needle holders

open access: yesCommunity Eye Health Journal, 2013
A needle holder, also called a needle driver (Figure 1), is made from stainless steel and is used to hold a suturing needle during surgical procedures.
Ismael Cordero
doaj  

A novel laparoscopic titanium purse-string forceps: application in animal experiments

open access: yesScientific Reports
Background Esophagojejunostomy (EJS) in laparoscopic total gastrectomy is a technically challenging and high-risk procedure. Current EJS techniques possess limitations, and an optimal solution remains uncertain.
Dong Zhang   +4 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Encapsulation process sterilizes and preserves surgical instruments [PDF]

open access: yes, 1964
Ethylene oxide is blended with an organic polymer to form a sterile material for encapsulating surgical instruments.
Morelli, F. A., Montgomery, L. C.
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Traceability of Surgical Instruments: A Systematic Review

open access: yesApplied Sciences
Objective: This study provides a comprehensive global overview of surgical instrument traceability systems and accentuates their growing importance in healthcare.
Moustafa Fayad   +7 more
doaj   +1 more source

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