Results 81 to 90 of about 4,695,534 (339)

William Arbuthnot Lane (1856-1943): Surgical Innovator and His Theory of Autointoxication. [PDF]

open access: yes, 2017
William Arbuthnot Lane contributed to the advancement of many fields of orthopedics, otolaryngology, and general surgery. He is credited for his no-touch technique and the invention of long-handled instruments, some of which are still in use today, to ...
Cowan, Scott W.   +4 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Standard operating procedures (SOP) in experimental stroke research: SOP for middle cerebral artery occlusion in the mouse [PDF]

open access: yes, 2012
Recently, systematic reviews have found quantitative evidence that low study quality may have introduced a bias into preclinical stroke research. Monitoring, auditing, and standard operating procedures (SOPs) are already key elements of quality control ...
Members of the MCAO-SOP Group   +1 more
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Care of ophthalmic surgical instruments

open access: yesCommunity Eye Health Journal, 2011
Good practice guidelines on handling and safety, maintenance and storage, transport, and security of surgical instruments.
Sue Stevens, Ingrid Mason
doaj  

A novel olecranon-type tracheotomy and expansion forceps for single-person emergency airway access

open access: yesFrontiers in Bioengineering and Biotechnology
BackgroundWe developed olecranon-type tracheotomy and expansion forceps (OTEF) for emergency tracheotomy in patients experiencing acute airway obstruction.
Liang Zhu   +8 more
doaj   +1 more source

Principles of Pituitary Surgery [PDF]

open access: yes, 2018
Key Points 1. Understand the principles of pituitary surgery including the key-elements of surgical planning and decision-making 2. Identify the technical nuances distinguishing the endoscopic from the microscopic transsphenoidal approach 3.
Evans, James J.   +4 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Inspecting and unbending surgical needle holders

open access: yesCommunity Eye Health Journal, 2013
A needle holder, also called a needle driver (Figure 1), is made from stainless steel and is used to hold a suturing needle during surgical procedures.
Ismael Cordero
doaj  

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