Results 111 to 120 of about 4,737,260 (339)

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

Digital localization of intraoperative samples enhances margin analysis precision in oral squamous cell carcinoma

Frontiers in Medicine
ObjectivesThe intraoperative margin assessment technique enhances local control of Oral Squamous Cell Carcinoma (OSCC). However, the standard frozen section analysis (FSA) procedure does not allow precise interpretation of the final histopathological ...
Adam Michcik, Adam Michcik, Aleksandra Ciarka, Aleksandra Ciarka, Łukasz Garbacewicz, Łukasz Garbacewicz, Adam Polcyn, Adam Polcyn, Piotr Choma, Barbara Wojciechowska, Barbara Wojciechowska, Barbara Drogoszewska, Barbara Drogoszewska   +12 more
doaj   +1 more source

Predictors of Surgical Margin Following Breast-Conserving Surgery: A Large Population-Based Cohort Study

Annals of Surgical Oncology, 2016
BackgroundThe purpose of this retrospective, population-based, cohort study was to identify patient and tumor characteristics that are associated with a high risk of tumor-positive margins after breast-conserving surgery (BCS) to optimize preoperative ...
C. V. van Deurzen
semanticscholar   +1 more source

Molecular markers in the surgical margin of oral carcinomas

, 2008
BACKGROUND: Local or regional lymph node recurrence is the most common pattern of treatment failure in oral squamous cell carcinoma (SCC). The local recurrence rate is 30% even when the surgical resection margin is diagnosed as tumour free.
Dabelsteen, E., Anders Bilde, Therkildsen, Marianne Hamilton, Dabelsteen, Erik, Dabelsteen, Sally, von Buchwald, Christian, Bilde, A., Dabelsteen, S., Buchwald, C. von, Christian Von Buchwald, Sally Dabelsteen, Erik Dabelsteen, Bilde, Anders, Therkildsen, M.H., Marianne Hamilton Therkildsen   +14 more
core   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez, Fareshte Erani, Katherine J. Bangen, David G. Coughlin, Douglas Galasko, Kelsey R. Thomas   +5 more
wiley   +1 more source

Ambient Ionization Mass Spectrometry for Cancer Diagnosis and Surgical Margin Evaluation

Clinical Chemistry, 2015
Background There is a clinical need for new technologies that would enable rapid disease diagnosis based on diagnostic molecular signatures. Ambient ionization mass spectrometry has revolutionized the means by which molecular information can be obtained ...
D. Ifa, L. Eberlin
semanticscholar   +1 more source

Surgical margins for soft tissue sarcoma [PDF]

Acta Orthopaedica Scandinavica, 1997
The Enneking classification of surgical margins is the only one which shows a reasonable correlation between the type of margin and the risk of local recurrence. However, it can be improved by a complementary definition of compartments and a better investigation of local tumor growth.
openaire   +2 more sources

Margin setting with high-frequency data [PDF]

Both in practice and in the academic literature, models for setting margin requirements in futures markets classically use daily closing price changes. However, as well documented by research on high-frequency data, financial markets have recently shown ...
Cotter, John, Longin, Francois
core  

Risk Factors of Surgical Site Infection at Muhimbili National Hospital, Dar es Salaam, Tanzania [PDF]

, 2012
Surgical site infection (SSI) is a common source of morbidity among operated patients. At Muhimbili National Hospital (MNH), studies indicate that the rate of SSI has been increasing over the past thirty years.
Mbembati, NM, Akoko, L.O., Fredrick, F, Mbembati, N.M., Akoko, LO, Mwanga, AH, Fredrick, F., Mwanga, A.H.   +7 more
core   +1 more source

Diffusion Basis Spectrum Imaging of Tissue Microstructure and Early Treatment in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Conventional MRI cannot resolve the coexisting pathological processes within multiple sclerosis tissue. Diffusion Basis Spectrum Imaging decomposes the diffusion signal into fiber, cell, and hindered ratios indexing axonal integrity, cellularity, and extracellular space, respectively.
Apisit Kaewsanit, Aime Luna, Bradley Judge, Nicole Shelley, Karl Friedrichsen, Jayashree Rajamanickam, Zhude Tu, Yong Wang, Tammie L. S. Benzinger, Qing Wang, Matthew R. Brier   +10 more
wiley   +1 more source