A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues +6 more
wiley +1 more source
Analysis on the application of a CT-guided medical adhesive-based localization method in sublobectomy to ensure surgical margins. [PDF]
Yu S +9 more
europepmc +1 more source
Nipple‑sparing mastectomies: Clinical outcomes from a single academic institution [PDF]
Conant, Leah +5 more
core +2 more sources
Understanding the Effects of Conductive Polymer Electrode Coating on Recorded Neural Signals
Conductive polymer coatings are widely explored to improve the quality of signals recorded with chronically implanted neural electrodes, offering enhanced biocompatibility along with reduced electrode impedance. Combining computational modelling and data from PEDOT:PTS coated and PtIr electrodes in rats, we show that improvements in signal quality with
Karthik Sridhar +4 more
wiley +1 more source
Canady Helios Cold Plasma Induces Non-Thermal (24 °C), Non-Contact Irreversible Electroporation and Selective Tumor Cell Death at Surgical Margins. [PDF]
Murthy SRK +6 more
europepmc +1 more source
Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar +7 more
wiley +1 more source
Prognostic significance of surgical margins in open neck horizontal laryngectomy: a systematic review and meta-analysis. [PDF]
Crosetti E +9 more
europepmc +1 more source
Hybrid Nanofibers for Multimodal Accelerated Wound Healing
Fabrication of wound healing scaffolds based on biocompatible nanofibers. Nanofibers offering high surface area, flexibility, and biocompatibility significantly improved the healing outcome in vivo. Histological, immunological, and anti‐inflammatory markers are noticeably better in treated wounds.
Viraj P. Nirwan +15 more
wiley +1 more source
The impact of histology and molecular biology in refining the prognostic value of surgical margins in head and neck oncology - A narrative review. [PDF]
Morbini P +7 more
europepmc +1 more source

