Results 31 to 40 of about 101,410 (263)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Surgical treatment of hiatal hernia: A ten-year experience [PDF]

open access: yesVojnosanitetski Pregled, 2018
Background/Aim. Today, hiatal hernia and the accompanying gastroesophageal reflux disease (GERD) are the most common benign disorders of the upper gastrointestinal tract.
Korica Milan   +5 more
doaj   +1 more source

Modified Vaginal Mesh Procedure with DynaMesh®-PR4 for the Treatment of Anterior/Apical Vaginal Prolapse

open access: yesDiagnostics, 2023
(1) Background: Treating female pelvic organ prolapse (POP) is challenging. Surgical meshes have been used in transvaginal surgeries since the 1990s, but complications such as mesh exposure and infection have been reported. Polyvinylidene fluoride (PVDF)
Chia-Ju Lin   +4 more
doaj   +1 more source

Surgical Mesh as a Scaffold for Tissue Regeneration in the Esophagus [PDF]

open access: yesEuropean Surgical Research, 2004
<i>Background:</i> Textiles in the form of surgical meshes are widely used in hernia surgery. Their porous structure allows tissue infiltration to incorporate the fabric for complete healing and device stabilization. This study was aimed to reconstitute the esophageal wall and to investigate the functional and histological consequences of a
Petra, Lynen Jansen   +5 more
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

SECURING MESH WITH SKINSTAPLES VERSUS PROLENE SUTURE IN INGUINAL HERNIA REPAIR: EFFECTS ON POST-OPERATIVE COMPLICATIONS

open access: yesPakistan Armed Forces Medical Journal, 2020
Objective: To compare the frequency of surgical site infection, Seroma formation and urinary retention in patients undergoing Lichtenstein inguinal hernia repair using staples and polypropylene for securing the mesh.
Amir Khulique   +4 more
doaj   +4 more sources

Clinical characteristics of patients with inguinal hernia mesh migration into the bladder

open access: yesIJU Case Reports, 2022
Introduction We report two cases of mesh migration into the bladder after inguinal hernia surgery. Case presentation In the first case, a 48‐year‐old woman who underwent right internal inguinal hernia repair, 18 months prior, presented with pollakiuria ...
Takahiro Akimoto   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Comparison of Light weight and Heavy weight Prosthetic Mesh for Lichtenstein Repair of Inguinal Hernia [PDF]

open access: yesJournal of Sharif Medical & Dental College, 2023
Objective: To compare outcomes of lightweight mesh (LWM) versus heavyweight mesh (HWM) in inguinal hernia repair. Methodology: It was a quasi-experimental study done at the General Surgery Department of Federal Government Polyclinic Hospital, Islamabad
Rehana Raza   +5 more
doaj  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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