Results 51 to 60 of about 1,372,626 (289)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

FastM: Design and Evaluation of a Fast Mobility Mechanism for Wireless Mesh Networks [PDF]

open access: yes, 2009
Although there is a large volume of work in the literature in terms of mobility approaches for Wireless Mesh Networks, usually these approaches introduce high latency in the handover process and do not support realtime services and applications. Moreover,
Couto, Luís   +3 more
core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Surgical treatment of hiatal hernia: A ten-year experience [PDF]

open access: yesVojnosanitetski Pregled, 2018
Background/Aim. Today, hiatal hernia and the accompanying gastroesophageal reflux disease (GERD) are the most common benign disorders of the upper gastrointestinal tract.
Korica Milan   +5 more
doaj   +1 more source

Modified Vaginal Mesh Procedure with DynaMesh®-PR4 for the Treatment of Anterior/Apical Vaginal Prolapse

open access: yesDiagnostics, 2023
(1) Background: Treating female pelvic organ prolapse (POP) is challenging. Surgical meshes have been used in transvaginal surgeries since the 1990s, but complications such as mesh exposure and infection have been reported. Polyvinylidene fluoride (PVDF)
Chia-Ju Lin   +4 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Clinical characteristics of patients with inguinal hernia mesh migration into the bladder

open access: yesIJU Case Reports, 2022
Introduction We report two cases of mesh migration into the bladder after inguinal hernia surgery. Case presentation In the first case, a 48‐year‐old woman who underwent right internal inguinal hernia repair, 18 months prior, presented with pollakiuria ...
Takahiro Akimoto   +5 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

SECURING MESH WITH SKINSTAPLES VERSUS PROLENE SUTURE IN INGUINAL HERNIA REPAIR: EFFECTS ON POST-OPERATIVE COMPLICATIONS

open access: yesPakistan Armed Forces Medical Journal, 2020
Objective: To compare the frequency of surgical site infection, Seroma formation and urinary retention in patients undergoing Lichtenstein inguinal hernia repair using staples and polypropylene for securing the mesh.
Amir Khulique   +4 more
doaj   +4 more sources

Comparison of Light weight and Heavy weight Prosthetic Mesh for Lichtenstein Repair of Inguinal Hernia [PDF]

open access: yesJournal of Sharif Medical & Dental College, 2023
Objective: To compare outcomes of lightweight mesh (LWM) versus heavyweight mesh (HWM) in inguinal hernia repair. Methodology: It was a quasi-experimental study done at the General Surgery Department of Federal Government Polyclinic Hospital, Islamabad
Rehana Raza   +5 more
doaj  

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