Results 91 to 100 of about 896,237 (268)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
5-Year Experience in Saliva Control Clinic in a Tertiary Center: Outcome of Drooling in Children
B-ENTBackground: Drooling beyond age 4 is pathological, requiring investigation and intervention. The lack of a standardized approach to treating children with drooling poses a challenge in managing these patients.
Jeyasakthy Saniasiaya +2 more
doaj +3 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Acta Obstetricia et Gynecologica ScandinavicaIntroduction The rate of vaginal hysterectomies is declining globally. We investigated surgical techniques, outcomes, and costs in a large national cohort of benign hysterectomies with prerequisites for vaginal surgery.
Johanna Wagenius +4 more
doaj +1 more source
Shanghai Jiaotong Daxue xuebao. Yixue banObjective·To quantify the volume of quadrigeminal cistern arachnoid cysts (QACs) and hydrocephalus indicators, and analyze the clinical features of QACs in children and the efficacy of different surgical techniques, with the goal of improving ...
Liu Meiling +5 more
doaj +1 more source
Surgical volume and clinical outcome
British Journal of Surgery, 2007 Centralise to ...
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
MedicinaBackground and Objectives: The selection of the optimal distal level of fusion in long-level fusion surgery remains controversial. Fusion ending at L5 preserves motion but increases the risk of L5–S1 disc degeneration.
Xiongjie Li +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source