Results 101 to 110 of about 3,580,327 (305)

A prospective study of spectrum of spinal dysraphisms and its surgical outcome

Journal of Spinal Surgery, 2015
Objective: To study the clinical profile of patients with spinal dysraphisms and the outcome of surgical interventions in these patients. Methodology: A total of 39 patients with spinal dysraphism were studied in a tertiary care setting during the period
Vishwanath Sidram, P C Chandra Kumar, Bellara Raghavendra, Vinayak Sangreshi   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

The Impact of Frailty on Surgical Outcome of Patients with Lumbar Spinal Canal Stenosis

Spine Surgery and Related Research
Introduction: Frailty is an important factor in surgical outcomes. The current study aimed to evaluate the effect of preoperative frailty on postoperative outcomes in older patients with lumbar spinal canal stenosis (LSCS).
Saiki Sugimoto, Sota Nagai, Kei Ito, Hiroki Takeda, Soya Kawabata, Takehiro Michikawa, Daiki Ikeda, Shinjiro Kaneko, Nobuyuki Fujita   +8 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Transcatheter versus surgical aortic-valve replacement in high-risk patients. [PDF]

, 2011
BACKGROUND: The use of transcatheter aortic-valve replacement has been shown to reduce mortality among high-risk patients with aortic stenosis who are not candidates for surgical replacement.
Makkar, Raj R, Samir Kapadia, Dewey, Todd, Pichard, Augusto D, Mack, Michael J, Vinod H. Thourani, Duolao Wang, Smith, Craig R, Webb, John G, Babaliaros, Vasilis, Moses, Jeffrey W, D. Craig Miller, Jeffrey W. Moses, Wang, Duolao, Craig R. Smith, Mathew Williams, Todd Dewey, Miller, D Craig, Michael J. Mack, John G. Webb, William N. Anderson, Tuzcu, E Murat, Thourani, Vinod H, Raj R. Makkar, Gregory P. Fontana, Svensson, Lars G, Kapadia, Samir, E. Murat Tuzcu, Paul Corso, Martin B. Leon, Williams, Mathew, Stuart J. Pocock, Bavaria, Joseph E, MD, Howard C. Herrmann, Augusto D. Pichard, Lars G. Svensson, Pocock, Stuart J, Jodi J. Akin, Joseph E. Bavaria, Fontana, Gregory P, Akin, Jodi J, Corso, Paul, Bavaria, Joseph E, Leon, Martin B, Herrmann, Howard C, PARTNER Trial Investigators, Anderson, William N, Vasilis Babaliaros   +47 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Functional Outcome of Shaft of Femur Fracture Fixation with Elastic Nail in Children Between 05 to 10 Years of Age

Proceedings
Introduction: Femoral fractures are one of the most common issues in the childrens population. Between 6-16 age, there's no strong agreement as to the favored therapy. The therapy of femoral fractures in children has progressively changed towards a more
Ammad Ahmed, Zahid Munir, Iftikhar Muhyuddin, Kashif Jamal, Adeel Hamid, Zaigham Habib, Shuja Uddin   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Functional outcome following direct repair or intervertebral fusion for adolescent spondylolysis : a systematic review [PDF]

, 2012
A systematic review of the literature was performed to establish whether direct repair of the pars defect or intervertebral fusion achieves better Oswestry Disability Index scores in adolescent spondylolysis or low-grade spondylolisthesis.
Cooke, Stephen J., Westacott, Daniel J.
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source