Results 61 to 70 of about 126,973 (265)

SHORT-TERM CLINICAL OUTCOMES OF AWAKE AND OUTPATIENT TRANSFORAMINAL ENDOSCOPIC LUMBAR FORAMINOTOMY AND INTERSPINOUS SPACER DEVICE [PDF]

Coluna/Columna
Objective: To evaluate the clinical outcomes achieved with the combined surgical management of Transforaminal Endoscopic Lumbar Foraminoplasty (TELF) with an Interspinous Spacer Device (ISD) in patients with DS grades I and II and LSS.
Jorge Felipe Ramírez León, Yetzalis Antonieta Fernández Vera, Carolina Ramírez Martínez, José Gabriel Rugeles Ortíz, Nicolás Prada Ramírez, Viviana Marcela Plazas Bedoya, João Paulo Machado Bergamaschi, Gabriel Oswaldo Alonso Cuéllar   +7 more
doaj   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

ADAMKIEWICZ’S ARTERY IN ENDOSCOPIC SURGERY: NARRATIVE REVIEW [PDF]

Coluna/Columna
Endoscopic spine surgery has become increasingly popular among specialized surgeons, driven by its minimally invasive approach and increasing clinical versatility.
Renan Herbert Ferreira, Daniel Ferreira Ghedini, Cleanto Moreira de Lacerda, Thiago Queiroz Soares, Ariel Falbel Lugão, Álvaro Dowling Montalva, Sonja Ellen Lobo, João Paulo Machado Bergamaschi   +7 more
doaj   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Minimally invasive cardiac surgical procedures in female population

Journal-Cardiovascular Surgery, 2014
With the development of minimally invasive cardiac surgical procedures in recent years, many minimal incisions have been used to perform operations on patients with heart diseases. In this study, we documented our experience with limited skin incisions for congenital heart diseases, pericardial disease and cardiac tumors.
Ferit Cicekoglu, Seyhan Babaroglu, Onur Hanedan, Murat Songur, Garip Altintas, Kerem Yay   +5 more
openaire   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Adoption, Outcomes, and Healthcare Professionals’ Perceptions of Minimally Invasive Surgical Techniques in Neonatology and Pediatric Surgery: A Clinical Study

Journal of Pharmacy and Bioallied Sciences
Background: Minimally invasive surgical techniques have revolutionized neonatology and pediatric surgery by offering less traumatic procedures with reduced recovery times and improved outcomes.
Abhishek Ranjan, Shyam S. Sahu, Abhishek K. Singh, Kiran S. Das, Prita N. Dubraj, Priya S. Lakra   +5 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source