Results 71 to 80 of about 126,973 (265)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Pilon Fractures: Update on treatment

Journal of the Foot & Ankle
Tibial pilon fractures (plafond) are severe injuries resulting from predominately axial impaction. They are typically accompanied by severe damage to the vulnerable soft tissue envelope and the articular damage, making these fractures prone to ...
Franco Mombello , German Vera, Stefan Rammelt   +2 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Minimally Invasive Surgery: A Paradigm Shift in Surgical Procedures

International Journal of Innovative Science and Research Technology (IJISRT)
Minimally Invasive Surgery (MIS) and microsurgery have significantly transformed periodontal treatment by reducing tissue trauma and improving patient outcomes. MIS focuses on minimizing flap reflection and tissue manipulation, preserving blood supply, and ensuring the stability of blood clots at the wound site, which collectively reduce postoperative ...
Suchetha A, Aditi Gupta, Darshan BM, Sapna N, Apoorva SM, Dhrittisha Parag   +5 more
openaire   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Minimally Invasive Surgery for Juvenile Hallux Valgus

Journal of the Pediatric Orthopaedic Society of North America
In adults, minimally invasive surgery for surgical treatment of hallux valgus has become increasingly popular, with a growing body of literature showing safety and effectiveness comparable to open surgery.
Sang W. Lee, MSc, Daniel Gabriel, BS, Dong W. Lee, BS, Winnie T.H. Lin, MPH, Collin May, MD, MPH   +4 more
doaj   +1 more source

Videoscope-Assisted Minimally Invasive Surgery (VMIS) for Bone Regeneration around Teeth and Implants: A Literature Review and Technique Update

Dentistry Journal, 2018
Background—The literature related to minimally invasive periodontal surgery is reviewed. This includes the original minimally invasive surgery (MIS) procedure for bone regeneration, the modification of MIS for the minimally invasive surgery ...
Stephen K. Harrel
doaj   +1 more source

Minimally Invasive Cardiac Surgical Procedures in Children [PDF]

Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, 2020
openaire   +2 more sources

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source