Results 111 to 120 of about 1,137,204 (340)

Laparoscopic sleeve gastrectomy in adolescents with or without syndromic obesity: two years follow-up [PDF]

, 2017
Introduction Childhood obesity is an emerging health problem. Surgical treatment of obese adolescents, particularly those affected by congenital syndrome, represents a controversial issue.
ABBATINI, FRANCESCA, Brad Michael Watkins,, Emanuela Ceriati,, Francesco De Peppo,, IOSSA, ANGELO, Romina Caccamo,, SILECCHIA, Gianfranco   +6 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Tonsillectomy New Vistas [PDF]

History of tonsillectomy dates back to nearly 2000 years. It was Celsius who first\ud described the procedure in the first century A.D. The potentials for complications after this surgical\ud procedure are still very high despite the advancements in ...
Balasubramanian, Thiagarajan
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Reintervenciones quirúrgicas en el servicio de cirugía del hospital "Aleida Fernández Chardiet"

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
Fundamento: las relaparotomías pueden ser programadas o a demanda; esta última se decide acorde a la evolución posoperatoria del enfermo, el juicio clínico del especialista en cirugía y el equipo médico de apoyo.Objetivo: caracterizar las ...
Victor Manuel Sierra Alfonso
doaj  

Intraoperative Neurophysiological Monitoring for Endoscopic Endonasal Approaches to the Skull Base: A Technical Guide. [PDF]

, 2016
Intraoperative neurophysiological monitoring during endoscopic, endonasal approaches to the skull base is both feasible and safe. Numerous reports have recently emerged from the literature evaluating the efficacy of different neuromonitoring tests during
Doan, Adam T., Evans, James J., Kenning, Tyler J., Lober, Robert M., Matsumoto, Craig I., Singh, Harminder, Vogel, Richard W.   +6 more
core   +3 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Surgical site infection after caesarean section. Space for post-discharge surveillance improvements and reliable comparisons [PDF]

, 2016
Surgical site infections (SSI) after caesarean section (CS) represent a substantial health system concern. Surveying SSI has been associated with a reduction in SSI incidence.
Agresta, A., Allocca, A., Ascenzi, M. P., Ascenzi, M. P., Baccaro, G., Barboni, P., Beggiato, S., Belvisi, V., Bianchi, U., Bianchini, C., Cammarota, M., Carbone, A., Caterini, A., Cava, M. C., Celiberti, A., Ciavarella, M., Ciccotosto, N., Cicogna, V. A., Cimaglia, Claudia, Clerici Bagozzi, F., Colantuono, G., Colazingari, G., Conti, E., Curzi, M., Dalla Vecchia, D., Del Borgo, C., Ferraro, Federica, Fiore, R., Fioriello, C., Forino, F., Grilli, E., Ippolito, Giuseppe, La Mura, A., Lanini, S., Lucarelli, B., Manzi, P., Marrone, R., MARZUILLO, CAROLINA, Masala, P., MASTROIANNI, Claudio Maria, Mondillo, V., Montesano, P., Morgante, A. S., Moscardini, M. L., Moscatelli, M. M., Natalini Raponi, G., Orazi, D., Pallozzi, L., Panepuccia, L., Parrocchia, S., Pignataro, R., Piscioneri, C., Piselli, Pierluca, Pitorri, A., Pittalis, Silvia, Pizziconi, G., Primavera, A., Puro, Vincenzo, Quintavalle, G., Raponi, R., Rendo, V., Riccioni, C., Ruscitti, Luca E., Saccoccio, O., Salera, E., Salvati, O., Saviano, R., Serafini, G., Sguazzini, G., Silvestri, A., Soscia, F., Spaziani, C., Squarcione, S., Tana, M., Ullucci, M., Vagni, V., Verginelli, F., VILLARI, Paolo, VULLO, Vincenzo, Zaino, P., Zarelli, L.   +80 more
core  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

An Instructional Video to Improve Teaching Techniques and Learning in the Operating Room

MedEdPORTAL, 2009
Few physicians are given formal training in educational techniques, which is unfortunate because formal instruction on teaching has been shown to be effective and can improve the overall quality of the clerkship. Based on the premise that most physicians
Eric Sokol, William Metheny, Renee Ward
doaj   +1 more source