Results 121 to 130 of about 293,994 (314)

Abdominal integument atrophy after operative procedures

, 2012
The aim of the study was to analyze clinical material concerning postoperative atro‑ phy of abdominal integument. Material and methods: The evaluated group consisted of 29 patients with sonographically revealed atrophy of the abdominal wall.
Elżbieta Bernatowicz, Maria Gałdyńska, Katarzyna Kołaczyk, Stefania Bojko, Kołaczyk, Katarzyna, Gałdyńska, Maria, Bojko, Stefan, Smereczyński, Andrzej, Jan Lubiński, Bernatowicz, Elżbieta, Andrzej Smereczyński, Lubiński, Jan   +11 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

The risk of post-operative complications in psoriasis and psoriatic arthritis patients on biologic therapy undergoing surgical procedures.

, 2015
BACKGROUND: There is limited evidence as to whether biologic therapy should be stopped or continued in patients with psoriasis and/or psoriatic arthritis (PsA) who are undergoing surgical procedures.
Bakkour, W, Chinoy, Hector; id_orcid, Griffiths, CEM, Warren, RB, Purssell, H   +4 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Novel penile circumcision suturing devices versus the shang ring for adult male circumcision: a prospective study

International Brazilian Journal of Urology
Introduction To evaluate the safety and efficacy of a novel penile circumcision suturing devices PCSD and Shang ring (SR) for circumcision in an adult population. Materials and Methods A total of 124 outpatients were randomly assigned to receive PCSD (
Hu Han, Da-wei Xie, Xiao-guang Zhou, Xiao-dong Zhang   +3 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Dehiscence of a Composite Aortic Graft and Pseudoan- eursym Late After a Bentall Operation

Journal of Tehran University Heart Center, 2015
A 32-year-old female patient with previous Bentall operation and mitral valve repair surgery due to severe aortic insufficiency, mitral valve insufficiency, and ascending aortic aneurysm was admitted to our hospital with serious dyspnea, fatigue, and ...
Hasan Alper-Gurbuz, Ahmet Baris-Durukan, Cem Yorgancioglu   +2 more
doaj  

Urethral duplication type influences on the complications rate and number of surgical procedures

International Brazilian Journal of Urology
Introduction: Urethral duplication is rare. Characterized by the presence of two urethral channels. This anomaly presents a great variety of clinical findings that depend on the type of duplication that often is associated with other anomalies. Material
Roberto Iglesias Lopes, Amilcar Martins Giron, Marcos Figueiredo Mello, Cristovao Machado Barbosa Neto, Joana dos Santos, Paulo Renato Marcelo Moscardi, Victor Srougi, Francisco Tibor Denes, Miguel Srougi   +8 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Safe surgery checklist: evaluation in a neotropical region

Revista do Colégio Brasileiro de Cirurgiões
Objective: assess patient responses and associated factors of items on a safe surgery checklist, and identify use before and after protocol implementation from the records.
GIULENA ROSA LEITE, MARLENE ANDRADE MARTINS, LUDMILA GREGO MAIA, MARCO TÚLIO ANTONIO GARCIA-ZAPATA   +3 more
doaj   +2 more sources