Results 141 to 150 of about 2,951,344 (295)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

A Retrospective Observational Study on the Eleganza Protocol: A Standardized Seven-Step Workflow for Combined Aesthetic Surgery. [PDF]

Cureus
Rodríguez-García FA, Melo-Ventura RE, Álvarez-Trejo H, Márquez-Villalobos FO, Dorado-Hernández E, García-Dávila G, Camarena-Macias AP, Torres-Salazar QL.   +7 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Intraoral Approach for Mandibular Resection with TMJ Disarticulation: Outcomes from a Case Series

Pesquisa Brasileira em Odontopediatria e Clínica Integrada
Objective: To describe the tactical alterations that allow the use of the intraoral approach for resection of mandibular tumors requiring TMJ disarticulation.
André Gustavo Góes da Silva, Elenisa Glaucia Ferreira dos Santos, Emerllyn Shayane Martins de Araújo, Tatiane Fonseca Faro, Fernanda Souto Maior dos Santos Araújo, Allan Vinícius Martins-de-Barros, Fábio Andrey da Costa Araújo   +6 more
doaj  

Impact of surgical start time on clinical outcomes in urologic surgery: a single-center study of major oncologic surgeries and adrenalectomy. [PDF]

World J Urol
Kobatake K, Goto K, Kohada Y, Naito M, Miyamoto S, Sekino Y, Kitano H, Hieda K, Hinata N.   +8 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Experience of biological implants in thoracic surgery for soft tissue and chest wall reconstruction in clean and contaminated environments. [PDF]

J Thorac Dis
Jesani H, Surendrakumar V, Walji H, Ahmed M, Hernandez-Arenas L, Socci L, Martin-Ucar A.   +6 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Factors predicting operative exposure among UK urology trainees: a national analysis from 2010 to 2024. [PDF]

BJU Int
Tai JCJ, Ong K, Graham S, Royle J, Tien T.   +4 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source